Gustatory dysfunction in relation to circumvallate papilla/von ebner{u2019}s gland complex (CP/VEG) structure upon maxillary molars extraction in wistar rats / An animal study : Sana Mostafa Hussein Mohamed Elmogheer ; Supervised Amal Mohammed Elmotayam , Heba Mohammad Hakam

Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Biology

Background: The interaction between taste sensation and dentoalveolar sensation is still under research. Teeth loss can alter taste thresholds in humans, but the underlying mechanisms are still obscure. This study investigated the effect of unilateral maxillary molars extraction on the structure of circumvallate papilla in rats. Methods: Thirty two male Wister rats, aged 3-4 months were randomly distributed into four groups (one control and 3 experimental) each including 8 animals . The rats were euthanized 3, 6 or 9 weeks following the procedure. The changes in trough length and the taste buds structure and number of both sides of CVP were investigated using routine histological examination followed by statistical analysis. Results: the trough toward the extraction side was obviously shorter with noticeable decrease of taste buds{u2019} number than the non-extraction side. Taste buds were reduced in size and most of them showed signs of degeneration which was more evident in group II followed by group III. Less deformity detected in group IV in comparison to the preceding 2 experimental groups. the non-extraction side of all experimental groups showed normal trough length and generally normal histology of taste buds

Issued also as CD