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The possible protective role of mango (mangifera indica L.) polysaccharides against cyclophosphamide toxicity in male albino rats / Sara Mohamed Hassan Elaskalany ; Supervised Fathi Mohamed Abdelgleel , Ahmed Ibrahim Amein , Sohair Ramadan Fahmy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sara Mohamed Hassan Elaskalany , 2016Description: 129 P. : charts ; 25cmOther title:
  • الدور الوقائى المحتمل للسكريات المتعددة المستخلصة من المانجو ضد سمية السيكلوفوسفاميد فى ذكور الجرذان البيضاء [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry Summary: The present study aims to evaluate the possible protective role of polysaccharides extracted from the Egyptian mango mangifera indica L. (MPS) against cyclophosphamide (CP) hepatotoxicity and nephrotoxicity in male albino rats. The MPS revealed significant protective effect against liver and kidney injuries as demonstrated by enhancement of their function parameters as well as histopathological findings. The observed data also showed the antioxidant effect of MPS by decreasing the level of malondialdehyde (MDA) and increasing the level of reduced glutathione (GSH) as well as normalized the activities of the antioxidant enzyme glutathione-S-transferase (GST) and superoxide dismutase (SOD). In conclusion, the recorded results of the present study support the protective role of MPS and silymarin against CP- induced hepatic and renal damage
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.M.Sc.2016.Sa.P (Browse shelf(Opens below)) Not for loan 01010110071139000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.M.Sc.2016.Sa.P (Browse shelf(Opens below)) 71139.CD Not for loan 01020110071139000

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biochemistry

The present study aims to evaluate the possible protective role of polysaccharides extracted from the Egyptian mango mangifera indica L. (MPS) against cyclophosphamide (CP) hepatotoxicity and nephrotoxicity in male albino rats. The MPS revealed significant protective effect against liver and kidney injuries as demonstrated by enhancement of their function parameters as well as histopathological findings. The observed data also showed the antioxidant effect of MPS by decreasing the level of malondialdehyde (MDA) and increasing the level of reduced glutathione (GSH) as well as normalized the activities of the antioxidant enzyme glutathione-S-transferase (GST) and superoxide dismutase (SOD). In conclusion, the recorded results of the present study support the protective role of MPS and silymarin against CP- induced hepatic and renal damage

Issued also as CD

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