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Upfront surgical management of wilms' tumor / Ahmed Mohammed Abdelaziz Elsarawy ; Supervised Osama Elmalt , Alaa Elhaddad , Alaa Younes

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ahmed Mohammed Abdelaziz Elsarawy , 2015Description: 151 P. : facsimiles ; 25cmOther title:
  • العلاج الجراحى الاستباقى {uئإإ٠} (ورم ويلمز) عند الأطفال [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology - Surgical Summary: Over the past decades, 2 different approaches for the treatment of Wilms tumor have emerged: upfront nephrectomy (UN) and preoperative chemotherapy (PC), with adjuvant treatment adjusted to stage, histology, and chemotherapy response. Data from the international society of pediatric oncology (SIOP) suggested decreased intraoperative spillage and more feasible surgery after PC. The children oncology Group (COG) has adopted the concept of UN assuming the feasibility of the resectional surgery and the proper staging information that may be lost with the administration of PC. Patients with unilateral renal masses diagnosed as WT who presented to the children cancer hospital of Egypt (CCHE) from January 2009 to January 2012, were subjected to UN with the exclusion of those who are not amenable to this approach based on the proposed COG protocol, to be treated first by chemotherapy. One hundred seven patients were identified (35 PC and 72 UN). Preoperative chemotherapy had more incidences of surgical complications. Intestinal obstruction was the most common post operative complication. Event free survival and overall survival were 76.8% and 79.9% for PC at 30 months vs 87.5% and 95.8% for UN at 36 months
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.Ph.D.2015.Ah.U (Browse shelf(Opens below)) Not for loan 01010110068599000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.Ph.D.2015.Ah.U (Browse shelf(Opens below)) 68599.CD Not for loan 01020110068599000

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology - Surgical

Over the past decades, 2 different approaches for the treatment of Wilms tumor have emerged: upfront nephrectomy (UN) and preoperative chemotherapy (PC), with adjuvant treatment adjusted to stage, histology, and chemotherapy response. Data from the international society of pediatric oncology (SIOP) suggested decreased intraoperative spillage and more feasible surgery after PC. The children oncology Group (COG) has adopted the concept of UN assuming the feasibility of the resectional surgery and the proper staging information that may be lost with the administration of PC. Patients with unilateral renal masses diagnosed as WT who presented to the children cancer hospital of Egypt (CCHE) from January 2009 to January 2012, were subjected to UN with the exclusion of those who are not amenable to this approach based on the proposed COG protocol, to be treated first by chemotherapy. One hundred seven patients were identified (35 PC and 72 UN). Preoperative chemotherapy had more incidences of surgical complications. Intestinal obstruction was the most common post operative complication. Event free survival and overall survival were 76.8% and 79.9% for PC at 30 months vs 87.5% and 95.8% for UN at 36 months

Issued also as CD

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