Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine

Objectives: The purpose of the study was to evaluate the validity of using internal jugular vein (IJV) diameter and collapsibility as a reliable index of fluid responsiveness in patients with sepsis. Methods: Hemodynamic data of patients with sepsis were collected before and after IV fluid bolus (7ml/kg) coupled with transthoracic echo to evaluate stroke volume variation before and after fluid bolus and ultrasound evaluation of IJV diameter and collapsibility (ratio of the difference between IJV maximal antero-posterior diameter and minimum diameter to minimum diameter x100). Patients were retrospectively divided into two groups; fluid responders (R), if CI increase of more than or equal to 15% after a 7ml/kg crystalloid infusion, and non-responders (NR). We compared differences in measured variables between R and NR groups and calculated receiver-operator-characteristic (ROC) curves of optimal IJV diameter and collapsibility and change in stroke volume sensitivity and specificity to predicting R

Issued also as CD