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Study of growth differentiation factor 15 expression in patients with beta thalassemia intermedia / Rania Mohamed Wagdy Salah Eldeen ; Supervised Mona Hassan Eltagy , Dalia Said Mossalam , Nadia Ibrahim Sewelam

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Rania Mohamed Wagdy Salah Eldeen , 2014Description: 143 P. : charts ; 25cmOther title:
  • فى حالات انيميا البحر المتوسط GDF15دراسة [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Background: The thalassemia syndromes represent the most common causes of ineffective erythropoiesis . The increased but ineffective erythropoiesis resulting in tissue iron overload induces numerous endocrine diseases, hepatic cirrhosis, cardiac failure and even death . Objectives: we aim to study GDF15 levels in Ý- thalassemia intermedia patients and to correlate its level to their iron status and different clinical and laboratory disease parameters. Method: This is case control study conducted on 25 pediatric patients under 18 years with beta thalassemia intermedia and 30 healthy children taken as control group . GDF 15 level was performed using ( ELISA) kit in serum samples that obtained from children of both groups . Abdominal examination , frequency of blood transfusion , Complete blood picture , Reticulocytic count , liver function tests , serum ferritin were done in case group to assess severity of beta thalassemia intermedia
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Ra.S (Browse shelf(Opens below)) Not for loan 01010110065761000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2014.Ra.S (Browse shelf(Opens below)) 65761.CD Not for loan 01020110065761000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: The thalassemia syndromes represent the most common causes of ineffective erythropoiesis . The increased but ineffective erythropoiesis resulting in tissue iron overload induces numerous endocrine diseases, hepatic cirrhosis, cardiac failure and even death . Objectives: we aim to study GDF15 levels in Ý- thalassemia intermedia patients and to correlate its level to their iron status and different clinical and laboratory disease parameters. Method: This is case control study conducted on 25 pediatric patients under 18 years with beta thalassemia intermedia and 30 healthy children taken as control group . GDF 15 level was performed using ( ELISA) kit in serum samples that obtained from children of both groups . Abdominal examination , frequency of blood transfusion , Complete blood picture , Reticulocytic count , liver function tests , serum ferritin were done in case group to assess severity of beta thalassemia intermedia

Issued also as CD

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