Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics

The purpose of this study was designed to explore the value of middle cerebral artery and umbilical artery Doppler indices in assessment of fetal wellbeing and prediction of neonatal outcome in pregnant women with IUGR and in pregnant women with preeclampsia. PATIENT AND METHODS: One hundred and twenty one (121) pregnant women were categorized into 4 groups; Group A: Preeclampsia without IUGR group (38 cases); Group B: IUGR without preeclampsia group (24 cases); Group C: Preeclampsia complicated with IUGR group (19 cases); Group D: Control group (40 cases). The perinatal outcomes correlated to the results of UA and MCA Doppler Indices, and CPR. The accuracy of UA and MCA Doppler Indices and CPR in the prediction of adverse outcome were calculated. RESULTS: Adverse neonatal outcome in group A was significantly correlated to UA-RI and UA-PI (r = 0.537, P-value < 0.001, and r = 0.405, P = 0.0116, respectively). However it showed no significant correlation with other parameter of Doppler indices and CPR. In group B, it was significantly correlated to all Doppler parameters indices and CPR. UA-RI and CPR were stronger parameters, to predict adverse neonatal outcome, than other parametes, with r-value = 0.869 and 0.803 respectively. In group C, it was significantly correlated to UA-RI and UA-PI, MCA-RI, and CPR

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