Monocyte CD 40 expression in sepsis and the effect of interferon gamma administration on outcome / Aly makram abdrabo Aly Habib ; Supervised HosamEldin Ahmed Mowafy , Sanaa Sayed Abd El Shafy , Hassan Samier Effat
Language: Eng Publication details: Cairo : Aly makram abdrabo Aly Habib , 2006Description: 230P : ill ; 30cmOther title:- اظهار سى دى 40 على سطح خلية المونوسايت فى حالات التقيح الدموى و تاثير اعطاء الانترفيرون جاما على الناتج [Added title page title]
- Issued also as CD
Item type | Current library | Home library | Call number | Status | Date due | Barcode | |
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Thesis | قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.09.Ph.D.2006.Al.M. (Browse shelf(Opens below)) | Not for loan | 01010110046084000 | ||
CD - Rom | مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.09.Ph.D.2006.Al.M. (Browse shelf(Opens below)) | Not for loan | 01020110046084000 |
Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Critical Care Medicine
Sepsis induces an early inflammatory cascade initiated by the innate immune responseThis often results in the development of multisystem organ failureCD40 is a cell surface protein belonging to the tumor necrosis factor (TNF) receptor familyLigation of monocyte CD40 by the T cell - derived CD40 ligand can trigger the production of various mediators , the transcription and activation of enzymes , and the upregulation of costimulatory molecules involved in the pathogenesis of sepsisInterferon gamma (INF - ?) is a major activator of monocytes that increase their antigen presenting capacityAdministration of (INF - ?) has been shown to decrease infectionThe aim of this work was to test the CD40 expression on monocyte as an objective tool to detect sepsis in ICU patients and the effect of (INF - ?) administration on improving survival
Issued also as CD
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