Thesis (M.Sc.) -Cairo University, 2024.

Bibliography: pages 82-92.

An applicable liquid chromatography-tandem mass spectrometry (LC-MS/MS) method is developed to enable the efficient residue detection of fifteen acidic pesticides in water (drinking, ground, irrigating, and agricultural drainage water) and ten acidic pesticides in soil. The extraction and sample concentration were accomplished using the solid-phase extraction (SPE) technique in water, and using QuEChERS method in soil. The pesticides were determined using the negative ESI-LC-MS/MS technique. The developed methods were fully validated according to the EU validation guidelines. The accuracy and precision calculations were evaluated by sample fortifications at concentrations of 0.1, 0.5, 1.0 µg/L in water, and at concentrations of 0.01,0.5, 0.1 µg/ml in soil. Acceptable recoveries and precisions were obtained of 70–120% and below 20%, respectively. The methods showed good linearity ( from 0.995 to 0.999). The developed method quantitation limits were 0.1 µg/L for most of the studied pesticides in water and 0.01 µg/ml for all studied pesticides in soil. Furthermore, a one-year survey was conducted by collecting 108 water samples from different water sources in Egypt and 24 soil samples during the period between June 2020 and May 2021. The obtained results showed the absence of residues for most of the acidic pesticides in the collected water and soil samples, except for bentazone which was present in 33% of the collected water samples with a concentration range of 0.1 to 0.29 µg/L, and Bromoxynil which was present in one collected soil sample from Behera at concentration 0.3 µg/ml

تم تطوير طريقة باستخدام جهاز(LC-MS/MS) للكشف الفعال عن بقايا خمسة عشر مبيدًا حمضيًا في المياه و التربة. و استخلاص وتركيز العينة باستخدام تقنية استخلاص الطور الصلب (SPE) في الماء وطريقة QuEChERS في التربة. والتحقق من صحة الطرق المطورة وفقًا لإرشادات التحقق في الاتحاد الأوروبي.، تم إجراء تقصي لمدة عام من خلال جمع 108 عينة مياه من مصادر مياه مختلفة في مصر و24 عينة تربة من محافتي الجيزة والبحيرة خلال الفترة من يونيو 2020 إلى مايو 2021. النتائج التي تم الحصول عليها عدم وجود بقايا لمعظم باستثناء البنتازون الذي تواجد في عينات المياه المجمعة بتركيز 0.1 إلى 0.29 ميكروجرام/لتر، والبروموكسينيل الذي وجد في عينة تربة اخذت من البحيرة بتركيز 0.3 ميكروجرام/مل.

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