Thesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Application in Medical and Biological

This study was performed to detect the effect of Aculaser on spasticity in children with spastic cerebral palsy. Sixty spastic cerebral palsy children with their age ranging between 1 and 4 years old (mean age 2.57 ± 1.3) were included in the current study. They were distributed into three equal groups according to the clinical types of spastic cerebral palsy; Hemiplegia, Diplegia and Quadriplegia groups, each group contained 20 children and subdivided into two equal subgroups; control and study subgroups, each subgroup contained 10 children. Pre and post treatment evaluation was applied to the sixty children including the following variables; muscle tone of the wrist flexors & ankle planter flexors, range of motion of wrist flexion & extension and ankle planter flexion & dorsiflexion, and the gross motor function measure (GMFM). Pretreatment evaluation was applied just prior starting the treatment of the individual child, and the post treatment evaluation was applied immediately after the end of the study period of each individual child (3 months). The control subgroups have received the physiotherapy program of cerebral palsy 3 times per week for successive 3 months, while the study subgroups have received the same physiotherapy program with the same frequency and period in addition to the iv application of Aculaser twice per week for successive 3 months

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