Thesis (M.Sc.)-Cairo University, 2023.

Bibliography: pages 70-79.

Background: Active management of the third stage of labour is common practice today that leads to significant decrease in postpartum hemorrhage and maternal peripartum mortality and morbidity rates.
Objective: Evaluation of the efficacy of intraumbilical injection versus intravenous infusion of oxytocin in management of third stage of labor.
Patients and Methods: A total of 80 pregnant women were enrolled, after consenting each of them and divided into two groups; group A (control group) included 40 women received intravenous injection of 20 units of oxytocin diluted in on 500 ml saline infusion and group B (study group) included 40 women who received intraumblical injection of 10 units oxytocin in 10 ml saline (umbilical vein). Study groups were compared as regard duration of delivery of the placenta, amount of post partum blood loss, incidence of retained placenta, possible complications of the technique and compliance of the patient.
Results: Time needed for placental separation was shorter 17.95±6.29 vs. 19.60±6.15 mins., postoperative hemoglobin and heamatocrit reductions and estimated blood loss were lesser 0.70±0.32 vs. 1.29±0.33 g/dl, 2.01±0.48 vs. 2.69±0.39 % and 145.65±8.97 vs. 153.10±8.41 ml respectively among cases who received intraumbilical injection of oxytocin. Also, need for blood transfusion and incidence of retained placenta were lower 5 (12.5%) vs. 8 (20.0%) and 4 (10.0%) vs. 6 (15.0%) among cases who received intraumbilical injection of oxytocin compared with intravenous group.
Conclusion: Intraumbilical route is painless, safer and easier, and its prophylactic use during labor is recommended due to the good results obtained and the satisfactory prognosis in the puerperium.

تم خلال هذه الدراسة تسجيل 80 امرأة حامل، بعد موافقة كل واحدة منهن، وتم تقسيمهن إلى مجموعتين؛ المجموعة أ (المجموعة الضابطة) شملت 40 امرأة تلقين حقنة وريدية من 20 وحدة من الأوكسيتوسين المخفف في 500 مل من محلول ملحي والمجموعة ب (مجموعة الدراسة) شملت 40 امرأة تلقين حقنة داخل الحبل السري من 10 وحدات من الأوكسيتوسين في 10 مل محلول ملحي (الوريد السري). تمت مقارنة مجموعات الدراسة فيما يتعلق بمدة ولادة المشيمة، وكمية فقدان الدم بعد الولادة، وحدوث المشيمة المحتبسة، والمضاعفات المحتملة للتقنية وامتثال المريضة.
أظهرت دراستنا عدم وجود فروق ذات دلالة إحصائية بين مجموعات الدراسة فيما يتعلق بجميع معايير الدراسة ولكن الحقن داخل الحبل السري لمجموعة الأوكسيتوسين أظهر نتائج أفضل.

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