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The role of magnetic resonance spectroscopy in the diagnosis of dementia / Karim Hany Mohamed Hafez Sherif ; Supervised Kareem Mohamed Mohsen Moussa , Hassan Saad Hosny

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Karim Hany Mohamed Hafez Sherif , 2020Description: 132 P . : charts , facsmilies ; 25cmOther title:
  • قيمة الرنين المغناطيسى الطيفى فى تشخيص القصور الذهنى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis Summary: Background: Dementia is not a specific disease. It's an overall term that describes a group of symptoms associated with a decline in memory or other thinking skills severe enough to reduce a person's ability to perform everyday activities. Aim and objectives: The purpose of this study was to prove that MRS study of elderly patients with dementia will show a specific biomarker pattern of dementia patients and that MRS will be a beneficial diagnostic added value compared to other investigations. Subjects and methods: This was a case control study of a total of 40 patients. 20 neurologically confirmed dementia patients and 20 controls neurologically free population in Kasr Al-Aini teaching hospital. They all underwent MRS to measure metabolic changes in dementia and compare it with healthy subjects. Patients were classified into 2 groups: group (A): including 20 neurologically normal patients, and group (B): including 20 neurologically referred dementia patients from Kasr Al Ainy neurology department Results: Patient{u2018}s MRI diagnosis in Group (A) show that all patients had normal MRI findings and corresponding MRS values while in Group (B) their was a statistically significant difference between groups MRS values, and there were statistically significant differences between groups where P<0.001as regard each of MRS metabolites, mainly decrease in the NAA/Cr ratio in group B
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.31.M.Sc.2020.Ka.R (Browse shelf(Opens below)) Not for loan 01010110083646000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.31.M.Sc.2020.Ka.R (Browse shelf(Opens below)) 83646.CD Not for loan 01020110083646000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis

Background: Dementia is not a specific disease. It's an overall term that describes a group of symptoms associated with a decline in memory or other thinking skills severe enough to reduce a person's ability to perform everyday activities. Aim and objectives: The purpose of this study was to prove that MRS study of elderly patients with dementia will show a specific biomarker pattern of dementia patients and that MRS will be a beneficial diagnostic added value compared to other investigations. Subjects and methods: This was a case control study of a total of 40 patients. 20 neurologically confirmed dementia patients and 20 controls neurologically free population in Kasr Al-Aini teaching hospital. They all underwent MRS to measure metabolic changes in dementia and compare it with healthy subjects. Patients were classified into 2 groups: group (A): including 20 neurologically normal patients, and group (B): including 20 neurologically referred dementia patients from Kasr Al Ainy neurology department Results: Patient{u2018}s MRI diagnosis in Group (A) show that all patients had normal MRI findings and corresponding MRS values while in Group (B) their was a statistically significant difference between groups MRS values, and there were statistically significant differences between groups where P<0.001as regard each of MRS metabolites, mainly decrease in the NAA/Cr ratio in group B

Issued also as CD

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