Thesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Forensic Medicine and Clinical Toxicology

Background: opioids are recognized as necessary and legitimate agents to treat pain but are associated with significant risks to patients and society that include misuse, abuse, diversion, addiction and overdose deaths. aim of work: aim of this study is to study the management, sociodemographic factors and substance abuse among patients admitted with acute opiates toxicity to national environmental and clinical toxicology and research center (NECTR), cairo university hospitals during the period of the study. the outcome of this work will help in improving the outcome of patients admitted with acute opiates toxicity and recognizing the magnitude of the problem on statistical basis. subjects and methods: this prospective study included 98 cases who were admitted to nectr from october 2020 to march 2021, they were classified into 3 age groups; (less than 20 years), (20-40 years) and (more than 40 years). data were analyzed with respect to socio demographic data of the patients, substance of abuse, manner of intake, history of addiction, clinical presentation, management and outcome. results: the most common age group was those between 20-40 years (67.3%) followed by those above 40 years (22.4%) with male dominance (82.7%). the most common substance of abuse was opiates 63.3% (62 patients).the most common manner of overdose was accidental (95.9%) and the mortality rate was (11.7%). conclusions: males were more common than females. most common substance of abuse was opiates

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