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Detection of mutations in FLT3 and jak-2 genes in patients with different subtypes of acute myeloid leukemia / Aida Kamal Ahmed ; Supervised Magda Noshy , Magda M. Asem , Ghada M. Elsayed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Aida Kamal Ahmed , 2012Description: 119 P. : charts , facsimiles ; 25cmOther title:
  • تحديد الطفرات بجيني أف ال تي ٣ و الجاك٢ في مرضي الانواع المختلفة من سرطان الدم الميلودي الحاد [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology Summary: The FLT3 gene is mutated by an internal tandem duplication (ITD) in 20-25% of adults with acute myeloid leukemia (AML). Recently, a few patients with AML were found to have the JAK2 V617F mutation. These gene mutations cause constitutive activation of the receptor, in the absence of ligand. This study aimed to assess the frequency of FLT3/ITD and JAK2 V617F mutations in a cohort of 194 newly diagnosed de novo acute myeloid leukmeia AML patients
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.M.Sc.2012.Ai.D (Browse shelf(Opens below)) Not for loan 01010110060588000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.M.Sc.2012.Ai.D (Browse shelf(Opens below)) 60588.CD Not for loan 01020110060588000

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology

The FLT3 gene is mutated by an internal tandem duplication (ITD) in 20-25% of adults with acute myeloid leukemia (AML). Recently, a few patients with AML were found to have the JAK2 V617F mutation. These gene mutations cause constitutive activation of the receptor, in the absence of ligand. This study aimed to assess the frequency of FLT3/ITD and JAK2 V617F mutations in a cohort of 194 newly diagnosed de novo acute myeloid leukmeia AML patients

Issued also as CD

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