The role of cyclin D1 as a possible prognostic marker for papillary thyroid carcinoma : A histopathological and immunohistochemical study / Manar Mohamed Hany Hafez ; Supervised Hany Mahmoud Khattab , Samar Abdelmonem Elsheikh , Mohamed Faisal Ibrahim Darweesh
Material type: TextLanguage: English Publication details: Cairo : Manar Mohamed Hany Hafez , 2014Description: 118 P. : charts , facsimiles ; 25cmOther title:- التعبير عن ال"سايكلين د-1" و علاقته بسرطان الغدة الدرقية الحليمي : دراسة كيميائية هستومناعية [Added title page title]
- Issued also as CD
Item type | Current library | Home library | Call number | Copy number | Status | Date due | Barcode | |
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Thesis | قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.27.M.Sc.2014.Ma.R (Browse shelf(Opens below)) | Not for loan | 01010110063746000 | |||
CD - Rom | مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.27.M.Sc.2014.Ma.R (Browse shelf(Opens below)) | 63746.CD | Not for loan | 01020110063746000 |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology
Cyclin D1 protein was studied in 40 papillary thyroid cancer (PTC) patients including 24 cases of the conventional type, 12 cases of its follicular variant and four cases of papillary microcarcinoma retrieved as routinely processed paraffin blocks taken from the department of Pathology, Kasr El Ainy Hospital. For all specimens, some clinical data were available on the computer files including age and sex of the patients, tumor size, tumor focality, histopathological variant, presence of extrathyroidal extension and lymph node metastasis. Cell cycle progression is facilitated by Cyclin dependent kinases (CDKs) that are activated by cyclins, including Cyclin D1 and inhibited by CDK inhibitors. Evidence of the involvement of Cyclin gene alterations and overexpression of various cyclins in human cancer is growing. The role of Cyclin D1 in malignant progression of papillary carcinomas of the thyroid has yet to be established
Issued also as CD
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