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Studying the effect of low power diode laser in combination with bone graft and platelet rich fibrin on healing of periodontal intrabony defects : A randomized controlled clinical and experimental trial / Shrief Hemaid Mostafa Ahmad Hemaid ; Supervised Ali Mohamed Saafan , Manal Mohamed Hosny , Med. Gernot Wimmer

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Shrief Hemaid Mostafa Ahmad Hemaid , 2019Description: 103 P . : charts , facsmilies , photographs , 25cmOther title:
  • دراسة تأثير ليزر الدايود المنخفض الشدة و المستخدم مع الرقع العظمية و الألياف الغنية بالصفائح الدموية علي التئام العيوب اللثوية داخل العظم طريقة سريرية و تجريبية عشوائية المراقبة [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Applications in Oral Surgery Summary: Background: Low-level laser therapy (LLLT) has shown a positive local biostimulative effect in the early stage of bone healing. Aims: This study aimed to evaluate the healing of periodontal intrabony defects by the effect of low power Diode (808nm) laser therapy in combination with Nanohydroxyapatite bone graft and autologous Platelet Rich Fibrin compared to the effect of the combined treatment of Nanohydroxyapatite bone graft and autologous Platelet Rich Fibrin only without laser on induced periodontal intrabony defects in rabbits and on periodontal intrabony defects in human. Materials and Methods: The study was conducted experimentally on 16 defects in 8 adult male rabbits (n=16) divided into 4 groups; [Control non- treated group (C), laser irradiated nontreated group (CL), Non-irradiated Treated with nanograft and PRF (G+PRF) and Irradiated Treated group (G+PRF+L)]. And it also was conducted on 18 Humans (n=18) divided on 3 groups; [Non-irradiated Treated with nanograft and PRF group (Group1), Buccally laser irradiated and treated group (Group2) and Buccal and lingual irradiated and treated group (Group3). The animal defects were induced in the form of one osseous wall defects of 10 mm height, 4 mm depth between the 1st and the 2nd molars using a tapered FG drill coupled to a high-speed motor. Assessment: For animals, CT radiography was made at baseline, 15 and 30 days later for the living animals and a histological study was made at the 15th and 30th days. While for the humans, clinical assessment at baseline and after 3, 6, 9 and 12 M (including; PI, PPD, BOP, and CAL), Lab. Assessment for GCF ALP; at baseline and after, 3M, 6M, 9M and 12 M and Radiographic assessment; by CbCT at baseline and after 12 M). Statistical analysis using ANOVA was done for the obtained clinical, laboratory and radiographical data blind stud
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.24.04.Ph.D.2019.Sh.S (Browse shelf(Opens below)) Not for loan 01010110081277000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.24.04.Ph.D.2019.Sh.S (Browse shelf(Opens below)) 81277.CD Not for loan 01020110081277000

Thesis (Ph.D.) - Cairo University - National Institute of Laser Enhanced Sciences - Department of Laser Applications in Oral Surgery

Background: Low-level laser therapy (LLLT) has shown a positive local biostimulative effect in the early stage of bone healing. Aims: This study aimed to evaluate the healing of periodontal intrabony defects by the effect of low power Diode (808nm) laser therapy in combination with Nanohydroxyapatite bone graft and autologous Platelet Rich Fibrin compared to the effect of the combined treatment of Nanohydroxyapatite bone graft and autologous Platelet Rich Fibrin only without laser on induced periodontal intrabony defects in rabbits and on periodontal intrabony defects in human. Materials and Methods: The study was conducted experimentally on 16 defects in 8 adult male rabbits (n=16) divided into 4 groups; [Control non- treated group (C), laser irradiated nontreated group (CL), Non-irradiated Treated with nanograft and PRF (G+PRF) and Irradiated Treated group (G+PRF+L)]. And it also was conducted on 18 Humans (n=18) divided on 3 groups; [Non-irradiated Treated with nanograft and PRF group (Group1), Buccally laser irradiated and treated group (Group2) and Buccal and lingual irradiated and treated group (Group3). The animal defects were induced in the form of one osseous wall defects of 10 mm height, 4 mm depth between the 1st and the 2nd molars using a tapered FG drill coupled to a high-speed motor. Assessment: For animals, CT radiography was made at baseline, 15 and 30 days later for the living animals and a histological study was made at the 15th and 30th days. While for the humans, clinical assessment at baseline and after 3, 6, 9 and 12 M (including; PI, PPD, BOP, and CAL), Lab. Assessment for GCF ALP; at baseline and after, 3M, 6M, 9M and 12 M and Radiographic assessment; by CbCT at baseline and after 12 M). Statistical analysis using ANOVA was done for the obtained clinical, laboratory and radiographical data blind stud

Issued also as CD

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