Malignant breast tumours : Role of MRI in predicting histopathological grading / Ziad Mahmoud Fouad Gad ; Supervised Maha Hussein Helal , Sahar Mahmoud Mansour , Mervat Mohamed Eldeftar

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Ziad Mahmoud Fouad Gad

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TextLanguage: English Publication details: Cairo : Ziad Mahmoud Fouad Gad , 2014Description: 90 Leaves : charts , facsimiles ; 25cmOther title:

أورام الثدى الخبيثة : دور الرنين المغناطيسى فى توقع الدرجة الهيستوباثولوجية [Added title page title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis Summary: To evaluate the correlation between dynamic MRI parameters and ADC values with histological grading in breast cancer. Thirty patients with BIRADS V lesions on mammography were included in the study. MRI examination included conventional sequences; diffusion weighted imaging and dynamic contrast enhanced magnetic resonance imaging. Morphological features, dynamic parameters, and ADC values were recorded and correlated with with the histological grades. A statistically significant inverse correlation between ADC value and histological grade was found. Tumors with higher grade showed lower ADC value compared with those of lower grade (p = 0.001). The mean ADC values of grade I, II and III were 0.96 ± 0.09 x 10⁻³ mm² / s, 0.89 ± 0.11 x 10⁻³ mm² /s and 0.76 ± 0.07 x 10⁻³ mm² / s, respectively. Also, high grade tumors (grade III) were more associated with washout dynamic curve compared to those with lower grades (grades I and II) (p = 0.04). However, no correlation was found between the maximum relative enhancement and the grade

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Item type	Current library	Home library	Call number	Copy number	Status	Date due	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.31.M.Sc.2014.Zi.M (Browse shelf(Opens below))		Not for loan		01010110065168000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.11.31.M.Sc.2014.Zi.M (Browse shelf(Opens below))	65168.CD	Not for loan		01020110065168000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis

To evaluate the correlation between dynamic MRI parameters and ADC values with histological grading in breast cancer. Thirty patients with BIRADS V lesions on mammography were included in the study. MRI examination included conventional sequences; diffusion weighted imaging and dynamic contrast enhanced magnetic resonance imaging. Morphological features, dynamic parameters, and ADC values were recorded and correlated with with the histological grades. A statistically significant inverse correlation between ADC value and histological grade was found. Tumors with higher grade showed lower ADC value compared with those of lower grade (p = 0.001). The mean ADC values of grade I, II and III were 0.96 ± 0.09 x 10⁻³ mm² / s, 0.89 ± 0.11 x 10⁻³ mm² /s and 0.76 ± 0.07 x 10⁻³ mm² / s, respectively. Also, high grade tumors (grade III) were more associated with washout dynamic curve compared to those with lower grades (grades I and II) (p = 0.04). However, no correlation was found between the maximum relative enhancement and the grade

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