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Plaque characterization by optical coherence tomography and correlation with clinical presentation / Mina Sami Halim Fawzy Youssef ; Supervised Mohammed Mahmoud Abdelghany , Amr Abdelaziz Elfaramawy , Khaled Abdelazim Shokry

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mina Sami Halim Fawzy Youssef , 2015Description: 118 P. : charts , facsimiles ; 25cmOther title:
  • التعرف على مورفولوجيا اللويحة بواسطة التصوير البصرى المقطعى و ارتباط هذا بالاستعلان السريرى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology Summary: Optical coherence tomography is a new intravascular imaging method with high resolution. This may allow us to assess the vulnerable plaques in detail in vivo. The aim of the present study was to evaluate the ability of optical coherence tomography (OCT) for assessment of plaque characteristics and vulnerability in patients with acute coronary syndrome compared to stable angina patients. Patients undergoing cardiac catheterization were enrolled and categorized according to their clinical presentation: recent acute coronary syndrome (ACS), or stable coronary artery disease (SCAD). OCT imaging was obtained using the commercially available frequency domain - OCT C7XR system and the dragonfly catheter (St Jude medical system, lightlab Imaging Inc., westford, massachusetts). Two observers independently analyzed the images using the previously validated criteria for plaque characterization. Of 48 patients enrolled, 27 with ACS, and 21 with SCAD. In the ACS, and SCAD groups, lipid-rich plaque (was observed in 96.3%, and 66.7%, respectively (P = 0.015). The median value of the minimum thickness of the fibrous cap was 70, and 100 om, respectively (P = 0.064). The frequency of thin - cap fibroatheroma (defined by lipid - rich plaque with cap thickness {u2264} 65 om) was 33.3%% in the ACS group, and 14.3% in the SCAD group (P = 0.185). No procedure - related complications occurred
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.M.Sc.2015.Mi.P (Browse shelf(Opens below)) Not for loan 01010110068327000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.M.Sc.2015.Mi.P (Browse shelf(Opens below)) 68327.CD Not for loan 01020110068327000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology

Optical coherence tomography is a new intravascular imaging method with high resolution. This may allow us to assess the vulnerable plaques in detail in vivo. The aim of the present study was to evaluate the ability of optical coherence tomography (OCT) for assessment of plaque characteristics and vulnerability in patients with acute coronary syndrome compared to stable angina patients. Patients undergoing cardiac catheterization were enrolled and categorized according to their clinical presentation: recent acute coronary syndrome (ACS), or stable coronary artery disease (SCAD). OCT imaging was obtained using the commercially available frequency domain - OCT C7XR system and the dragonfly catheter (St Jude medical system, lightlab Imaging Inc., westford, massachusetts). Two observers independently analyzed the images using the previously validated criteria for plaque characterization. Of 48 patients enrolled, 27 with ACS, and 21 with SCAD. In the ACS, and SCAD groups, lipid-rich plaque (was observed in 96.3%, and 66.7%, respectively (P = 0.015). The median value of the minimum thickness of the fibrous cap was 70, and 100 om, respectively (P = 0.064). The frequency of thin - cap fibroatheroma (defined by lipid - rich plaque with cap thickness {u2264} 65 om) was 33.3%% in the ACS group, and 14.3% in the SCAD group (P = 0.185). No procedure - related complications occurred

Issued also as CD

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