Anesthetic efficacy of 2% mepivacaine versus 4% articaine for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis in mandibular molars : A randomized clinical trial therapeutic study (MANBIP) part 9 / Mohamed Abdel Hafiz Elhousieny ; Supervised Manar Yehia Fouda , Marwa Mahmoud Bedier

Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Endodontics

This clinical study was conducted to assess the anesthetic efficacy of 2% Mepivacaine versus 4% Articaine for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis in mandibular molars during access cavity preparation and instrumentation. The study design was a randomized blinded clinical trial in which the study participants and assessor didn{u2019}t know which intervention has been received. Sixty-six patients with vital lower posterior teeth received single-visit root canal treatment using ProTaper Universal rotary system for canal preparation, they were randomly divided into two groups (n=33) according to the anesthetic solution used either Group M (3.6 ml mepivacaine hydrochloride 2% with 1:100000 epinephrine) or Group A (3.4 ml articaine hydrochloride 4% with 1:100000 epinephrine). The pain was assessed using numerical rating scale (NRS) during access cavity preparation and instrumentation and the need for supplemental anesthesia was also recorded. All demographic data and NRS scores obtained from patients were analyzed and the results showed similarity between both groups regarding age, gender distribution and tooth type. There was no difference in pain level between both groups in the NRS scores at the different observed times (During Access cavity preparation and During Instrumentation)

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