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Management of optic pathway gliomas in pediatric age group / Abdelrhman Enayet Abdelhamid ; Supervised Mohamed Hassan Nayel , Wael Mokhtar Elmahdy , Mostafa Zein Elabideen Ali

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Abdelrhman Enayet Abdelhamid , 2015Description: 159 P. : charts , facsimiles ; 25cmOther title:
  • علاج أورام السبيل البصرى بالاطفال [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Neurosurgery Summary: Optic pathway gliomas (OPG) are rare neoplasms in children with an unpredictable outcome. Because of their natural history and location there is much controversy about the optimal strategy of management of OPG. We aimed to present our experience in the management of children with optic pathway gliomas in the pediatric age group. Patients and results: Thirty seven patients (18 male/ 19 female) were included in this study, with a mean age of 5 years. OPG were chiasmatic (n=19), optic nerve (n=8), hypothalamic (n=5) and chiasmatic/hypothalamic (n=5). Six cases had NFI. Four cases were surgically debulked and 25 were biopsied (16 open, 8 stereotactic and one endoscopic) while 7 cases were totally excised. Seven out of 8 optic nerve tumors were managed by excision and the last one had no surgical intervention. Twenty six patients received chemotherapy. Histopathology revealed pilocytic (n=19), pilomyxoid (n=13), fibrillary astrocytoma (n=2) and grade I papillary-glioneuronal tumor (n=1). Patients suffered from visual affection (n=27), endocrine dysfunction (n=10) and diencephalon syndrome (n= 2). The event free survival rates at 1 and 2 years were , 88.3% and 83.4% respectively. The 2 years overall survival rate was 87.8%. (Mean follow-up duration = 21.5 months).
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.20.Ph.D.2015.Ab.M (Browse shelf(Opens below)) Not for loan 01010110066765000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.20.Ph.D.2015.Ab.M (Browse shelf(Opens below)) 66765.CD Not for loan 01020110066765000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Neurosurgery

Optic pathway gliomas (OPG) are rare neoplasms in children with an unpredictable outcome. Because of their natural history and location there is much controversy about the optimal strategy of management of OPG. We aimed to present our experience in the management of children with optic pathway gliomas in the pediatric age group. Patients and results: Thirty seven patients (18 male/ 19 female) were included in this study, with a mean age of 5 years. OPG were chiasmatic (n=19), optic nerve (n=8), hypothalamic (n=5) and chiasmatic/hypothalamic (n=5). Six cases had NFI. Four cases were surgically debulked and 25 were biopsied (16 open, 8 stereotactic and one endoscopic) while 7 cases were totally excised. Seven out of 8 optic nerve tumors were managed by excision and the last one had no surgical intervention. Twenty six patients received chemotherapy. Histopathology revealed pilocytic (n=19), pilomyxoid (n=13), fibrillary astrocytoma (n=2) and grade I papillary-glioneuronal tumor (n=1). Patients suffered from visual affection (n=27), endocrine dysfunction (n=10) and diencephalon syndrome (n= 2). The event free survival rates at 1 and 2 years were , 88.3% and 83.4% respectively. The 2 years overall survival rate was 87.8%. (Mean follow-up duration = 21.5 months).

Issued also as CD

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