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Molecular study of multiple tumor suppressor gene and epidermal growth factor receptor expressions in breast carcinomas / Ahmed Anwar Sayed Mohamed ; Supervised Sanaa Osman Abdallah , Afaf Abd El Halim Abd El Khalek , Motawa Eisa ElHousseini

By: Contributor(s): Language: Eng Publication details: Cairo : Ahmed Anwar Sayed Mohamed , 2005Description: 137p : ill ; 30cmOther title:
  • دراسة جزيئيه للتعرف على الجين المتعدد و المثبط و مستقبل عامل النمو الجلدى فى اورام الثدي [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (PH.D.) - Cairo University - Faculty Of Science - Department Of Biochemistry Summary: expression has been reported in cancer cell lines and in certain malignant neoplasmThis gene encodes a protein that function as a negative cell cycle regulator at G1 - S checkpointOverexpression of EGFR has been shown in human cancer and could serve as a target for diagnosis and therapy for malignancyThis study was conducted on 14 benign breast tissues taken as control and 36 breast cancer patientsRT - PCR and ELISA techniques were used for detection of p16 and EGFR respectivelyFurthermore a significant increase of p16 expression was observed in benign breast tissue compared to malignant breast one p< 0001Also , a significant increase of p16 expression was found in low grade , negative lymph node and in histological subtype IL{u00B4}ђ{u008ѕ}C
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.Ph.D.2005.Ah.M. (Browse shelf(Opens below)) Not for loan 01010110043445000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.02.Ph.D.2005.Ah.M. (Browse shelf(Opens below)) 43445.CD Not for loan 01020110043445000

Thesis (PH.D.) - Cairo University - Faculty Of Science - Department Of Biochemistry

expression has been reported in cancer cell lines and in certain malignant neoplasmThis gene encodes a protein that function as a negative cell cycle regulator at G1 - S checkpointOverexpression of EGFR has been shown in human cancer and could serve as a target for diagnosis and therapy for malignancyThis study was conducted on 14 benign breast tissues taken as control and 36 breast cancer patientsRT - PCR and ELISA techniques were used for detection of p16 and EGFR respectivelyFurthermore a significant increase of p16 expression was observed in benign breast tissue compared to malignant breast one p< 0001Also , a significant increase of p16 expression was found in low grade , negative lymph node and in histological subtype IL{u00B4}ђ{u008ѕ}C

Issued also as CD

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