Thesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Zoonoses

World health organization designated food-borne infections with antibiotic resistant pathogens as an emerging public health problem. According to the global estimates, the most common food-borne illness causes of bacterial diarrhea are campylobacter species. Poultry meat is the most common source for food-borne cases caused by campylobacter. Thus, to investigate the occurrence of campylobacter spp., with special concern to tetracycline resistance strains as well as those resist other antibiotics widely used in veterinary field, a total of 360 chicken cloacal swabs, 15 water samples and 50 stool specimens from persons in approximate contact with the examined chickens were gathered from different poultry farms and shops in Giza and Cairo governorates. Additionally, 80 stool samples from persons suffering from gastrointestinal disorders collected from private lab and AbuElrish hospital for children. Moreover, 480 poultry products samples were purchased from different poultry shops, supermarkets, grocery and retail stores in Giza and Cairo Governorates in Egypt. All the collected samples were subjected to bacteriological examination on mCCDA media then confirmed by PCR targeting 23S gene of Campylobacter spp. which evidenced 19 campylobacter isolates, with rates of 1.9% (7) in chicken cloacal swabs, 6% (5) in human stool specimens and 6.6% (1) in water samples as well as 1.3 % (6) in the examined poultry products

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