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Pattern, management and impact of chest metastasis on survival outcome of osteosarcoma patients, NCI Egypt / Nancy Nabil Kamel Israel ; Supervised Mohamed Fawzy Ibrahim , Ahmad Mohammed Kamel , Asmaa Ibrahim Abdelaziz Salama

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Nancy Nabil Kamel Israel , 2016Description: 163 P. : facsimiles ; 25cmOther title:
  • نمط و تأثير ثانويات الصدر على معدل حياة مرضى أورام العظام (الأوستيوساركوما) بالمعهد القومى للأورام بمصر [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology Summary: Osteosarcoma accounting for about 56 % of all bones cancers in individuals under the age of 20 years. Although the overall survival has improved dramatically, yet it remains a challenging disease especially in developing countries. Was to find the survival outcome in metastatic osteosarcoma and its correlation to different prognostic variables. Sixty one (61) of newly diagnosed OS patients who presented to national cancer institute, Cairo university, Egypt from January 2008 To December 2013 were considered eligible in this retrospective study, data of the included patients were collected, that included age, gender, primary tumor size, initial lung metastases, lung metastases features, and management approach of lung metastases. The 3 year PFS was found to be 3%. The 3 year OS was 20% with a median survival of 23 months. Analysis of data in our study revealed statistically significant positive correlation between PFS and resectability (p value < 0.007), and negative correlation found with time to local control (P value < 0.02), while other factors were insignificant. Positive correlation was found between OS and resectability of lung metastases (P value0.04), yet other factors showed no statistical significance
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.05.M.Sc.2016.Na.P (Browse shelf(Opens below)) Not for loan 01010110070182000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.05.M.Sc.2016.Na.P (Browse shelf(Opens below)) 70182.CD Not for loan 01020110070182000

Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology

Osteosarcoma accounting for about 56 % of all bones cancers in individuals under the age of 20 years. Although the overall survival has improved dramatically, yet it remains a challenging disease especially in developing countries. Was to find the survival outcome in metastatic osteosarcoma and its correlation to different prognostic variables. Sixty one (61) of newly diagnosed OS patients who presented to national cancer institute, Cairo university, Egypt from January 2008 To December 2013 were considered eligible in this retrospective study, data of the included patients were collected, that included age, gender, primary tumor size, initial lung metastases, lung metastases features, and management approach of lung metastases. The 3 year PFS was found to be 3%. The 3 year OS was 20% with a median survival of 23 months. Analysis of data in our study revealed statistically significant positive correlation between PFS and resectability (p value < 0.007), and negative correlation found with time to local control (P value < 0.02), while other factors were insignificant. Positive correlation was found between OS and resectability of lung metastases (P value0.04), yet other factors showed no statistical significance

Issued also as CD

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