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Further study in biologically active coumarins / Nehad Mohamad Aly Eldydamony ; Supervisied Sohair L. Elansary , Doaa E. Abdelrahman

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Nehad Mohamad Aly Eldydamony , 2016Description: 143 P. : charts ; 25cmOther title:
  • دراسة تكميلية للكومارينات ذات التأثير البيولوجي [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry Summary: Further Study in Biologically Active Coumarins Benzopyrones and furobenzopyrones are significant class of natural compounds isolated mainly from higher plants associated to Rutaceae families. They have a broad range and diversity of biological activities. Photochemotherapy designates a treatment method in which light of an appropriate wavelength is used to induce a therapeutic response in presence of photosensitizing drug such as PUVA. In this study, new intermediates and final benzopyrone, furobenzopyrones, tetrahydrobenzofurobenzopyrone and benzofurobenzopyrone derivatives were synthesized and screened for antibacterial and photosensitizing activities. Furthermore, docking study was undertaken to evaluate the binding affinity and orientation of compounds into the active sites of appropriate gyrase enzymes, compared with their antibacterial activity
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2016.Ne.F (Browse shelf(Opens below)) Not for loan 01010110072008000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2016.Ne.F (Browse shelf(Opens below)) 72008.CD Not for loan 01020110072008000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

Further Study in Biologically Active Coumarins Benzopyrones and furobenzopyrones are significant class of natural compounds isolated mainly from higher plants associated to Rutaceae families. They have a broad range and diversity of biological activities. Photochemotherapy designates a treatment method in which light of an appropriate wavelength is used to induce a therapeutic response in presence of photosensitizing drug such as PUVA. In this study, new intermediates and final benzopyrone, furobenzopyrones, tetrahydrobenzofurobenzopyrone and benzofurobenzopyrone derivatives were synthesized and screened for antibacterial and photosensitizing activities. Furthermore, docking study was undertaken to evaluate the binding affinity and orientation of compounds into the active sites of appropriate gyrase enzymes, compared with their antibacterial activity

Issued also as CD

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