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Study of the binding interaction of some drugs with serum albumin using spectroscopic methods and molecular docking / Noha Magdy Sayed Ahmed Elkhouly ; Supervised Marwa Ahmed Fouad , Suzan Mahmoud Soliman , Ahmed Mahmoud Elkerdawy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Noha Magdy Sayed Ahmed Elkhouly , 2021Description: 89 P. : charts , facsimiles ; 25cmOther title:
  • دراسة التفاعلات الارتباطية لبعض الأدوية مع الزلال المصلى باستخدام الطرق الطيفية والالتحام الجزيئى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry Summary: This thesis is concerned with studying the binding interaction of tropisetron with bovine serum albumin by using several spectroscopic techniques and molecular docking simulation. The thesis consists of the following sections: Section I: Introduction It includes: I. An overview about plasma protein binding, bovine serum albumin, different approaches for studying plasma protein binding, and investigated drugs. II. Literature review about the method of analysis for tropisetron, and the previously published approaches for studying plasma protein binding interactions.Section II: Aim of the work I. IT includes the aim of this work and the basis on which the work has been done. Section III: Spectroscopic methods This section is divided into 2 parts Part1: Experimental Part2: Results and Discussion Which includes: UV absorption measurement, Fluorescence spectroscopy measurements,Synchronous fluorescence spectroscopy, FT-IR analysis
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.M.Sc.2021.No.S (Browse shelf(Opens below)) Not for loan 01010110083474000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.M.Sc.2021.No.S (Browse shelf(Opens below)) 83474.CD Not for loan 01020110083474000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

This thesis is concerned with studying the binding interaction of tropisetron with bovine serum albumin by using several spectroscopic techniques and molecular docking simulation. The thesis consists of the following sections: Section I: Introduction It includes: I. An overview about plasma protein binding, bovine serum albumin, different approaches for studying plasma protein binding, and investigated drugs. II. Literature review about the method of analysis for tropisetron, and the previously published approaches for studying plasma protein binding interactions.Section II: Aim of the work I. IT includes the aim of this work and the basis on which the work has been done. Section III: Spectroscopic methods This section is divided into 2 parts Part1: Experimental Part2: Results and Discussion Which includes: UV absorption measurement, Fluorescence spectroscopy measurements,Synchronous fluorescence spectroscopy, FT-IR analysis

Issued also as CD

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