Relationship between women's body mass index and success rate of in vitro fertilization / Noura Mohamed Eltoukhi ; Supervised Hanan Fahmy Azzam , Mohamed Hany Shehata , Amel Shaaban Abdelmonem

Thesis (M.Sc.) - Cairo University - Faculty of Nursing - Department of Maternal and Newborn Health Nursing

Background: Infertility is considered a traumatic event, assisted reproductive technology is considered a revolution for infertility treatment, in vitro fertilization is the commonly performed procedure. Therefore, many factors affect procedure success, including body mass index. Aim of this study to explore the relationship between body mass index & in vitro fertilization success rate. Subject & methods: Design, a descriptive correlational prospective design was adopted. Sample; a total sample of 100 women underwent in vitro fertilization with age ranged from 25-35 years. The sample was recruited according to certain criteria. Women were classified into 6 groups regarding their body mass index, i.e., (underweight n=5), (normal weight n=9), (overweight n=36), (obese I n=32), (obese II n=14), and (obese III n=4). Setting: Private assisted reproductive technology center in Benha city in Qalyubia governorate. Tool: Women's Profile Questionnaire and state trait anxiety inventory were utilized. Results: the current study shows that 81% of women had primary infertility. There is a significant statistical correlation between the maternal body mass index, and medication doses, induction duration (F=1.122 at p=.354), cancellation rate ({²=26.386 at p=.003), number of embryos transfer ({²=18.032 at p=.054), chemical pregnancy ({²=14.985 at p=.010), implantation rate (F =3.264 at p=.009), and clinical pregnancy {² =17.873 at p=.003). However, the current study shows that women's body mass index has no effect on the number of aspirated ova ({²=15.215 at p=.436), fertilized ova (F=.561at p=.730), and ovulation induction side effects ({²=7.011 at p=.220). Conclusion: current study evaluated the relationship between body mass index, and in vitro fertilization success rate. The results show that doses of drugs for ovulation induction, the number of ovulation induction cycles, and, chemical pregnancy rate were negatively affected by body mass index. Besides, the higher implantation rate was associated with normal body weight, and the clinical pregnancy rate was lower in the obesity grade III than in other groups

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