Thesis (M.Sc.) - Cairo University - Faculty of Physical Therapy - Department of Growth and Development Disorders in Pediatrics

Background: Chronic kidney disease is associated with comorbid conditions that result in physical impairments. Objectives: Investigate balance impairments in children with chronic kidney disease (on home dialysis and non-hemodialysis) compared with typically developed age matched control group. Design: An observational design (cross-sectional study). Settings: The assessment procedures were conducted at the Nephrology Unit, Zagazig University Hospitals. Participants: Seventy-five children, age ranged from 8 to 15 years represented three groups of equal numbers; control group (typically developed), non-dialysis (stage 3 and 4) and hemodialysis group. Outcome measures:The Human assessment computer balance system was used to assess the limits of stability, center of pressure and sensory organization and balance. Results: Compared with typically developed children, those with CKD showed statistically significant low stability scores, greater path length and impaired sensory organization and balance (P<0.05). Furthermore, children on-hemodialysis showed significant impairments compared with non-dialysis group. Conclusion: Children with CKD exhibit poor postural stability regardless the cause and duration of the disease. Early ascertainment of these impairments is recommended to minimize the potentials for comorbidity in adulthood

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