Role Of Epidural Ketamine In Management Of Neuropathic Pain A Dose Response : Comparative Study With Epidural Morphine Compared To Standard Oral Treatment / Yasser Younis AbuSief Tolba ; Supervised Mahmoud Kamel Ahmed , Mohamed Abd El Hameed ElHag , Raafat Abd El Fattah Saeed
Language: Eng Publication details: Cairo : Yasser Younis AbuSief Tolba , 2005Description: 191P : ill ; 30cmOther title:- دور تعاطى عقار الكيتامين حول الام الجافية فى علاج الام مرض الاعصاب دراسة مقارنة مع عقار المورفين و العلاج المتداول عن طريق الفم [Added title page title]
- Issued also as CD
Item type | Current library | Home library | Call number | Copy number | Status | Date due | Barcode | |
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Thesis | قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.19.01.Ph.D.2005.Ya.R. (Browse shelf(Opens below)) | Not for loan | 01010110045047000 | |||
CD - Rom | مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.19.01.Ph.D.2005.Ya.R. (Browse shelf(Opens below)) | 45047.CD | Not for loan | 01020110045047000 |
Thesis (PH.D.) - Cairo University - National Cancer Institute - Department Of Anaesthesia and Pain Relief
Ketamine , an N - Methyl - D - Aspartate receptor antagonist , is known to be analgesic and to induce psychomimetic effectsNMDA receptors participate in the development and maintenance of pathologic pain after tissue injury : increased pain perception as a result of pain sensitization , in part from synaptic plasticityBenefits and risks of ketamine for the control of pain have studies for long timeIn this study systematically analysed randomised comparisons of ketamine with inactive controls and as adjuvant to opioids ; reporting on pain outcomes , opioid sparing , and adverse effects were performedData were combined using a fixed effect modelWeighted mean difference (WMD) for pain intensity (0 - 10 cm visual analogue scale) was ?089 cm at 6 h , ?042 at 12 h , ?035 at 24 h and ?027 at 48 hCumulative morphine consumption at 24 h was significantly decreased with ketamine (WMD ?157 mg) There was no difference in morphine - related adverse effectsThe other 37 trials tested in adults or children , prophylactic or therapeutic ketamine orally , intramuscularly , subcutaneously , intra - articulary , caudally , epidurally , transdermally
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