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Validated analytical methods for the determination of some Non-steroidal Anti-inflammatory drugs NSAIDs / Rajaa Tarek Darwich ; Supervsied Asmaa Ahmed Elzaher , Marianne Alphonse Mahrouse , Marwa Ahmed Fouad

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Rajaa Tarek Darwich , 2016Description: 146 Leaves ; 25cmOther title:
  • طرق تحليلية لتحديد بعض مضادات الالتهاب اللاستيرويدية و التحقق من صحتها [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry Summary: This thesis is concerned with the development of simple and accurate methods for the determination of some non- steroidal anti- inflammatory drugs (NSAIDs) in their pure and in pharmaceutical dosage forms. These drugs include ketorolac tromethamine, paracetamol and etodolac. Two HPLC methods using spectrophotometric detector for the determination of paracetamol, phenylephrine hydrochloride, ambroxol hydrochloride and levoceterizine dihydrochloride in their quaternary mixture and for the determination of phenylephrine hydrochloride, chlorpheniramine maleate and ketorolac Tromethamine in their ternary mixture. Application of TLC densitometric method, chemometric methods and ratio difference spectrophotometric method for the determination of ketorolac tromethamine and moxifloxacin hydrochloride in their binary mixture. Application of first derivative ratio spectrophotometric method, chemometric methods and dual wavelength spectrophotometric method for the determination of paracetamol and etodolac in their binary mixture. The proposed methods were validated and statistically compared with reference methods where no significant difference was found
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.M.Sc.2016.Ra.V (Browse shelf(Opens below)) Not for loan 01010110071657000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.M.Sc.2016.Ra.V (Browse shelf(Opens below)) 71657.CD Not for loan 01020110071657000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

This thesis is concerned with the development of simple and accurate methods for the determination of some non- steroidal anti- inflammatory drugs (NSAIDs) in their pure and in pharmaceutical dosage forms. These drugs include ketorolac tromethamine, paracetamol and etodolac. Two HPLC methods using spectrophotometric detector for the determination of paracetamol, phenylephrine hydrochloride, ambroxol hydrochloride and levoceterizine dihydrochloride in their quaternary mixture and for the determination of phenylephrine hydrochloride, chlorpheniramine maleate and ketorolac Tromethamine in their ternary mixture. Application of TLC densitometric method, chemometric methods and ratio difference spectrophotometric method for the determination of ketorolac tromethamine and moxifloxacin hydrochloride in their binary mixture. Application of first derivative ratio spectrophotometric method, chemometric methods and dual wavelength spectrophotometric method for the determination of paracetamol and etodolac in their binary mixture. The proposed methods were validated and statistically compared with reference methods where no significant difference was found

Issued also as CD

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