Comparison between subcision followed by 35% TCA versus subcision followed by microneedling in the treatment of acne scars : A prospective comparative study / Sarah Akram Kamal Hussein Orabi ; Supervised Amira Amin Zayed , Marwa Salah Eldin Elmesidy , Rasha Abdallah Abdlgghafar Ahmed

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology

Background: Acne scars treatment is difficult and challenging because of the variety in morphology and the limited ability of the available treatment options to improve the scars. Subcision is a non operative procedure that aims to break the fibrous strands that tether the scar to the underlying subcutaneous tissue.Chemical peeling is the application of chemicals to the skin surface aiming to destroy the damaged outer layers and accelerating the normal exfoliation process. Microneedling initiates collagen synthesis; this is achieved by causing minute injury to the dermis. For the optimal results, a tailored plan for each patient should be created specifically. Objectives: The aim of this study was to compare the efficacy and safety of both combined subcision and microneedling versus combined subcision and peeling in the treatment of acne scars. Patients and methods: Twenty patients with bilateral rolling and boxcar acne scars were enrolled. Subcision using microkeratomes on both sides of the face was done followed by 6 sessions of peeling using 35% TCA and micro needling with one month apart. In each session, half of the face was treated by peeling TCA 35% and the other half was treated by micro needling, randomly chosen. Evaluation of response was done by clinical assessment, ECCA grading scale and OCT imaging at baseline and 1 month after last session

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