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The prevalence of diabetes and prediabetes in first degree relatives of type 2 diabetes mellitus patients / Sara Nabil Boles Elkomos Ibrahim ; Supervised Mona Ahmed Radwan , Sameh Abdallah Eldewe Ahmed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sara Nabil Boles Elkomos Ibrahim , 2018Description: 86 P. : charts , facsimiles ; 25cmOther title:
  • دراسة مدى انتشار مرض السكرى و ماقبل السكرى ضمن الأقارب من الدرجة الأولى و مرضى السكرى من النوع الثانى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine Summary: Background: Type 2 DM is worldwide major health problem .Its prevalence has increased in recent decades. Prediabetes is considered to be a risk factor for further development of type 2DM. There is a complex interplay between genetic, epigenetic and environmental factors in incidence of type 2DM. Objective: Our aim of this prospective study was to determine the prevalence of T2DM and prediabetes in first degree relatives of type2 DM patients. Methods: This cross-sectional study included 300 individuals who are first degree relatives to type 2 DM patients aged 20 years and above and not known to be diabetic. They were subjected to physical examination and had assessment of HbA1c and blood lipids. Results: In this study, diabetic individuals were 16% among FDR of T2DM and prediabetic individuals were 19.3%. It was noticed that 46,2 % of the newly discovered hyperglycemic cases had only a diabetic mother. By linear regression, there were four predictors of HbA1c levels. They were TG levels, SBP measurements, age and weight. Conclusion: The FDR to T2DM patients are a major risk for prediabetes and T2DM
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.M.Sc.2018.Sa.P (Browse shelf(Opens below)) Not for loan 01010110077693000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.18.M.Sc.2018.Sa.P (Browse shelf(Opens below)) 77693.CD Not for loan 01020110077693000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Internal Medicine

Background: Type 2 DM is worldwide major health problem .Its prevalence has increased in recent decades. Prediabetes is considered to be a risk factor for further development of type 2DM. There is a complex interplay between genetic, epigenetic and environmental factors in incidence of type 2DM. Objective: Our aim of this prospective study was to determine the prevalence of T2DM and prediabetes in first degree relatives of type2 DM patients. Methods: This cross-sectional study included 300 individuals who are first degree relatives to type 2 DM patients aged 20 years and above and not known to be diabetic. They were subjected to physical examination and had assessment of HbA1c and blood lipids. Results: In this study, diabetic individuals were 16% among FDR of T2DM and prediabetic individuals were 19.3%. It was noticed that 46,2 % of the newly discovered hyperglycemic cases had only a diabetic mother. By linear regression, there were four predictors of HbA1c levels. They were TG levels, SBP measurements, age and weight. Conclusion: The FDR to T2DM patients are a major risk for prediabetes and T2DM

Issued also as CD

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