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Serum beta- 2 microglobulin level : A possible marker for disease progression in Egyptian patients with chronic HCV related liver diseases / Sarah Mahmoud Elsayed Ouda ; Supervised Mikhail Nasr Mikhail , Ashraf Elsayed Abdelhamied , Ahmed Mohamed Khairy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sarah Mahmoud Elsayed Ouda , 2014Description: 158 P. : charts ; 25cmOther title:
  • بيتا-2 ميكروجلوبيولين المصلى : دلالة ممكنة لتطور المرض عند المرضى المصريين المصابين بإلتهاب كبدى(ج) المزمن و أمراض الكبد المرتبطة بة [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology Summary: Beta - 2 microglobulin (v2M) is responsible for transmission of viral antigens on the surface of cells as part of HLA complex. Normal serum levels are less than 3æg / ml. It increases in inflammatory and malignant conditions including HCV infection. Determining the concentration of serum v2M levels in patients with HCV related chronic hepatitis, cirrhosis, and hepatocellular carcinoma and correlate the results with clinical parameters for disease progression. In this analytical cross sectional study 92 participants were included in 4 equal groups: Group (1) non cirrhotic chronic HCV, Group (2):HCV related liver cirrhosis, Group (3): HCC on top of HCV, Group (4): healthy controls. History taking, clinical examination ,routine labs, and US were done to all patients. Group specific inclusion criteria: PCR, metavir score for group (1) patients. CT and AFP for Group (3) patients. v2M levels were measured in serum by ELISA. Quantitative variables presented by number and percent were compared by chi - square or fisher's exact test
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.19.M.Sc.2014.Sa.S (Browse shelf(Opens below)) Not for loan 01010110066168000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.19.M.Sc.2014.Sa.S (Browse shelf(Opens below)) 66168.CD Not for loan 01020110066168000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology

Beta - 2 microglobulin (v2M) is responsible for transmission of viral antigens on the surface of cells as part of HLA complex. Normal serum levels are less than 3æg / ml. It increases in inflammatory and malignant conditions including HCV infection. Determining the concentration of serum v2M levels in patients with HCV related chronic hepatitis, cirrhosis, and hepatocellular carcinoma and correlate the results with clinical parameters for disease progression. In this analytical cross sectional study 92 participants were included in 4 equal groups: Group (1) non cirrhotic chronic HCV, Group (2):HCV related liver cirrhosis, Group (3): HCC on top of HCV, Group (4): healthy controls. History taking, clinical examination ,routine labs, and US were done to all patients. Group specific inclusion criteria: PCR, metavir score for group (1) patients. CT and AFP for Group (3) patients. v2M levels were measured in serum by ELISA. Quantitative variables presented by number and percent were compared by chi - square or fisher's exact test

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