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Penetration enhancing hybridized vesicles for the efficient ocular delivery of an anti-glaucoma drug / Sarah Saad Fayek Saad Naguib ; Supervised Samar Mansour Holayel , Rania Mohammed Hathout

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sarah Saad Fayek Saad Naguib , 2015Description: 111 Leaves : charts , photographs ; 30cmOther title:
  • حويصلات مهجنة محفزة للإختراق للإيتاء الفعال فى العين لعقار مضاد للجلوكوما [Added title page title]
Subject(s): Dissertation note: Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Technology Summary: The work in this thesis comprised the use of different hybrids of GRAS (generally regarded as safe) oils and surfactants in order to develop and optimize novel acetazolamide entrapped-vesicular systems aiming at improving its ocular delivery and reaching better therapeutic outcomes in the treatment of glaucoma. Accordingly, the phospholipid/cholesterol bilayer of the vesicles was enriched with hybrids of tween 80, labrasol, transcutol and labrafac lipophile WL in different masses and proportions according to a mixture design viz. D-optimal mixture design
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Thesis Thesis قاعة الثقاقات الاجنبية - الدور الثالث المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.34.M.Sc.2015.Sa.P (Browse shelf(Opens below)) Not for loan 01010110072289000

Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Technology

The work in this thesis comprised the use of different hybrids of GRAS (generally regarded as safe) oils and surfactants in order to develop and optimize novel acetazolamide entrapped-vesicular systems aiming at improving its ocular delivery and reaching better therapeutic outcomes in the treatment of glaucoma. Accordingly, the phospholipid/cholesterol bilayer of the vesicles was enriched with hybrids of tween 80, labrasol, transcutol and labrafac lipophile WL in different masses and proportions according to a mixture design viz. D-optimal mixture design

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