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Influence of hormonal and chemical anti - type- 2 diabetic drugs on immunological profile of Egyptian patients / Zeinab Saied Sayed Esawy ; Supervised Ahmed Mohamed Fathi Afifi , Azza Mohamed Elamir , Mohammed Hesham Elhefnawy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Zeinab Saied Sayed Esawy , 2018Description: 114 P. : charts , facsimiles ; 25cmOther title:
  • تأثير الأدوية الهرمونية والكيميائية المضادة للداء السكرى من النوع الثانى على المظهر المناعى للمرضى المصريين [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology (Physiology Immunology) Summary: Type 2 diabetes mellitus and its complications resulted from an activation of the innate immune system in the organs involved in glucose metabolism, Sulfonylurea and exogenous insulin have been used in the treatment of Type 2 diabetes, and they have hypoglycemic and anti-inflammatory effects. In this study we aimed to demonstrate the effect of sulfonylurea and exogenous insulin on some immunological parameters (WBCs, IL-6, IgG, and IgA) in Egyptian patients with T2DM and determine whether diabetes or the type of treatment would influence the levels of these parameters. All studied patients and control were subjected to estimate FBG, HbA1c, WBCs, IL-6, IgG and IgA.The results revealed that, sex and age have no effect on the levels of FBG, HbA1c, WBCs, IL-6, IgG and IgA of controls and diabetic patients groups. The FBG, HbA1c, WBCs, IL-6, IgG and IgA showed highly significant increase in the diabetic patient groups compared to controls.Treatment of T2DM patients with sulfonylurea and insulin caused highly significant decrease in the levels of FBG, HbA1c as compared to corresponding non-treated group
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.M.Sc.2018.Za.I (Browse shelf(Opens below)) Not for loan 01010110077945000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.21.M.Sc.2018.Za.I (Browse shelf(Opens below)) 77945.CD Not for loan 01020110077945000

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology (Physiology Immunology)

Type 2 diabetes mellitus and its complications resulted from an activation of the innate immune system in the organs involved in glucose metabolism, Sulfonylurea and exogenous insulin have been used in the treatment of Type 2 diabetes, and they have hypoglycemic and anti-inflammatory effects. In this study we aimed to demonstrate the effect of sulfonylurea and exogenous insulin on some immunological parameters (WBCs, IL-6, IgG, and IgA) in Egyptian patients with T2DM and determine whether diabetes or the type of treatment would influence the levels of these parameters. All studied patients and control were subjected to estimate FBG, HbA1c, WBCs, IL-6, IgG and IgA.The results revealed that, sex and age have no effect on the levels of FBG, HbA1c, WBCs, IL-6, IgG and IgA of controls and diabetic patients groups. The FBG, HbA1c, WBCs, IL-6, IgG and IgA showed highly significant increase in the diabetic patient groups compared to controls.Treatment of T2DM patients with sulfonylurea and insulin caused highly significant decrease in the levels of FBG, HbA1c as compared to corresponding non-treated group

Issued also as CD

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