Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Critical Care Medici Medicine

Before their use, many would die from simple yet unresolved infections (Aminov, 2010). Antimicrobials are those drugs that can treat a wide variety of diseases {u2013}Infectious diseases- by their ability to kill or inhibit the growth of microorganisms (NHS, 2015). In less than a century, oblivious mankind found itself in risk that could not be better entitled by the statement of WHO responsibles: "Antimicrobial resistance is a global health emergency that will seriously jeopardize progress in modern medicine, there is an urgent need for more investment in research and development for antibiotic-resistant infections including TB, otherwise we will be forced back to a time when people feared common infections and risked their lives from minor surgery{u2016} (WHO report Sep, 2017).In the last 50 years, drug resistance has emerged in many micro- organisms and that caused a reversal of some of the therapeutic miracles done by antimicrobials, limiting their efficacy and underscoring of disease prevention

Issued also as CD