The effect of acute lymphoblastic leukemia and chemotherapy on balance in children / Aya Ebrahim Mahmoud Elkomy ; Supervised Khaled Ahmed Olama , Hamada Elsayed Ayoub , Hossame Eldeen Ahmed Elashtokhy

Thesis (M.Sc.) - Cairo University - Faculty of Physical Therapy - Department of Growth and Development Disorders in Pediatrics

Introduction: Acute lymphoblastic leukemia is considered the most common form of malignancy in children with percentage of 29% of all childhood cancer, Chemotherapy is considered the first line of treatment in oncology despite its resulting side effects like peripheral neuropathy and problems involving cognition and behavior. Objectives: Assessment of the effect of acute lymphoblastic leukemia and chemotherapy on balance in children. Patients and Methods: this study was carried out on fifty children with acute lymphoblastic leukemia with ages varies from 5 to 11 years , they were selected from Tanta cancer center , they were divided according to the stage of treatment to three groups, group A : it includes ten children who were diagnosed by acute lymphoblastic leukemia, but before having any treatment , group B: it includes twenty children in the maintenance phase of treatment and group C: it includes twenty children in their first year of follow up , Humac balance system was used for balance assessment through three tests: the modified clinical test of sensory integration of balance , the limit of stability test and center of pressure test, and their measurements were compared to normal children matching in age and gender. Results: the results had shown no significant difference in the tests measurements of the acute lymphoblastic leukemic children when compared to normal children

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