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Effect of intra articular corticosteroid injections on temporomandibular joint structure : Experimental study / Asmaa Mahmoud Abdelhamid Salem Ghazal ; Supervised Atef Abdelhamid Fouda , Amany Hussien Nemat

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Asmaa Mahmoud Abdelhamid Salem Ghazal , 2014Description: 73 P. : photographs ; 25cmOther title:
  • تأثير حقن الكورتيزون داخل المفصل على بنيه مفصل الفك : دراسة تجريبية [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Surgery Summary: Temporomandibular joint and muscle disorders are a group of conditions that cause pain and dysfunction in the jaw joint and the muscles that control jaw movement. Intra - articular injections are one of the methods that physicians may use to treat joint pain. Corticosteroids were the first substances to be injected commonly into the intra articular space; corticosteroids were found to lower indicators of the inflammatory response. The indications and effectiveness of intra-articular steroid injections have been debated since their introduction. This study conducted on 36 rats whom injected by Depo-Medrol in the temporomandibular joint which is normally functioning joint. The rats were divided into three groups: A, B, and C. every group is divided into (2) sub groups. Each sub group had (6) rats; so the groups and the sub groups are: Group A: A₁, A₂ - Group B: B1, B₂ - Group C: C₁, C₂ All rats of the group A were injected one time, A₁ were sacrificed after (1) week from injection; A₂ were sacrificed after (2) weeks from injection. All rats of the group B were injected two times at (0, 6) weeks, B₁ were sacrificed after (1) week from last injection, B2 were sacrificed after (2) weeks from last injection. All rats of the group C were injected three times at (0, 6, and 12) weeks, C₁ were sacrificed after (1) week from last injection; C₂ were sacrificed after (2) weeks from last injection. All the specimens examined histological by light microscope after staining with Haematoxlin and Eosin; which showed affection of bone trabeculae and widening of marrow spaces in both the condylar head and temporal bone, the content of marrow spaces filled with fibrous tissues and no inflammatory cells in the beginning of injection but with more injections signs of inflammatory invasion and fatty degeneration appeared and presence of reversal line which represent new bone formation, no bone resorption, no changes in the disc and retrodiscal tissues
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.13.M.Sc.2014.As.E (Browse shelf(Opens below)) Not for loan 01010110069310000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.13.M.Sc.2014.As.E (Browse shelf(Opens below)) 69310.CD Not for loan 01020110069310000

Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Surgery

Temporomandibular joint and muscle disorders are a group of conditions that cause pain and dysfunction in the jaw joint and the muscles that control jaw movement. Intra - articular injections are one of the methods that physicians may use to treat joint pain. Corticosteroids were the first substances to be injected commonly into the intra articular space; corticosteroids were found to lower indicators of the inflammatory response. The indications and effectiveness of intra-articular steroid injections have been debated since their introduction. This study conducted on 36 rats whom injected by Depo-Medrol in the temporomandibular joint which is normally functioning joint. The rats were divided into three groups: A, B, and C. every group is divided into (2) sub groups. Each sub group had (6) rats; so the groups and the sub groups are: Group A: A₁, A₂ - Group B: B1, B₂ - Group C: C₁, C₂ All rats of the group A were injected one time, A₁ were sacrificed after (1) week from injection; A₂ were sacrificed after (2) weeks from injection. All rats of the group B were injected two times at (0, 6) weeks, B₁ were sacrificed after (1) week from last injection, B2 were sacrificed after (2) weeks from last injection. All rats of the group C were injected three times at (0, 6, and 12) weeks, C₁ were sacrificed after (1) week from last injection; C₂ were sacrificed after (2) weeks from last injection. All the specimens examined histological by light microscope after staining with Haematoxlin and Eosin; which showed affection of bone trabeculae and widening of marrow spaces in both the condylar head and temporal bone, the content of marrow spaces filled with fibrous tissues and no inflammatory cells in the beginning of injection but with more injections signs of inflammatory invasion and fatty degeneration appeared and presence of reversal line which represent new bone formation, no bone resorption, no changes in the disc and retrodiscal tissues

Issued also as CD

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