Thesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Operative Dentistry

The current study was conducted to compare the effect of color change between remineralizing agent and guided enamel regeneration in treatment of white spot lesion after orthodontic treatments. Materials & methods: in split mouth design, white spot lesions in anteriorteeth of post orthodontic debanding patients received randomly two types ofremineralizing agents, either Curodont Repair (self-assembling peptide p11-4) or Duraphat Fluoride varnish single dose, both materials were applied according tothe manufacturer{u2019}s instructions. White spot lesions were evaluated before andafter 3, 6 months follow up periods by two blinded assessors to assess patientsatisfaction using VAS score and color change by Vita Easyhshade. Results: Friedmann test was used to compare between follow-up periods forvisual analogue scale (VAS). A p-value less than or equal to 0.05 was consideredstatistically significant The patient satisfaction showed statistically significantdifference after application of Curodont Repair for 3 & 6 months follow up periods;in contrast with the results of Duraphat which record patient un satisfactionfor color change of white spot lesion. However repeated ANOVA was used toshow the effect of materials and follow-up periods. The color change of white spot lesions after application of both materials showed statistically significant difference with Curodont Repair for 6 months record results lower than that of Duraphat, this means better color change using Curodont Repair in treatment of white spot lesion

Issued also as CD