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Role of serum (1,3)-Ý-D-glucan assay in early diagnosis of invasive f ungal infection in pediatric intensive care unit / Huda Ibrahim Suliman Hegazy ; Supervised Hala Mohammed Fouad , Hebat Allah Fadel Elgebaly , Doaa Mohammed Ghaith

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Huda Ibrahim Suliman Hegazy , 2020Description: 95 P. : charts , facsimiles ; 25cmOther title:
  • دور مادة (3,1) -بيتا- د -جلوكان فى التشخيص المبكر للعدوى الفطرية الغازية فى وحدة الرعايه المركزة للأطفال [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: This study shows that critically ill children are at high risk of developing invasive fungal infection in a pediatric intensive care unit. Delaying the appropriate antifungal treatment of Invasive Candidiasis (IC) while awaiting blood culture results has been associated with increased hospital mortality. The Candida score is a useful tool to differentiate critically ill patients, who would benefit from early antifungal treatment (score >3), from those in whom invasive candidiasis is highly improbable (score {u2264}3). One of the developed biomarkers is (1,3)-Ý-D-Glucan (BG), which is a major cell wall component of almost all fungi except for Zygomycetes and Cryptococcus species. Various studies measured different sensitivity and specificity of (1,3)-Ý-D-Glucan (BG)substance
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2020.Hu.R (Browse shelf(Opens below)) Not for loan 01010110081157000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2020.Hu.R (Browse shelf(Opens below)) 81157.CD Not for loan 01020110081157000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

This study shows that critically ill children are at high risk of developing invasive fungal infection in a pediatric intensive care unit. Delaying the appropriate antifungal treatment of Invasive Candidiasis (IC) while awaiting blood culture results has been associated with increased hospital mortality. The Candida score is a useful tool to differentiate critically ill patients, who would benefit from early antifungal treatment (score >3), from those in whom invasive candidiasis is highly improbable (score {u2264}3). One of the developed biomarkers is (1,3)-Ý-D-Glucan (BG), which is a major cell wall component of almost all fungi except for Zygomycetes and Cryptococcus species. Various studies measured different sensitivity and specificity of (1,3)-Ý-D-Glucan (BG)substance

Issued also as CD

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