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Study of the potential of arachidonic acid to naturally eradicate schistosoma / Violette Said Hanna Youssef ; Supervised Ebtisam Abdelaziz Hafez , Azza Mahmoud Gawish , Hatem Abdelmoneim Tallima

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Violette Said Hanna Youssef , 2018Description: 100 P. : photographs ; 25cmOther title:
  • دراسة قدرة حمض الاراكيدونيك على التخلص الطبيعى من دودة البلهارسيا [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology Summary: Schistosoma mansoni and Schistosoma haematobium are parasitic flatworms that infect millions of people in developing countries. A recent report has proved that resistance of the water-rat to S. mansoni might be ascribed to arachidonic acid (ARA)-rich lipids in liver. Reports have shown that ARA is a safe and effective schistosomicide in vitro, and in vivo. Accordingly, it was proposed that ARA increased levels might be responsible for natural attrition of S. mansoni and S. haematobium in resistant rodents. Therefore, the levels of ARA in serum, lung, and liver of rats (resistant) and mice (susceptible) before and post infection with S. mansoni and between mice (semi-permissive) and hamster (susceptible) before and post infection with S. haematobium were compared. Significant (P<0.05) correlation was recorded between ARA content and rodent resistance to schistosomes, implicating ARA as an endoschistosomicide
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.25.M.Sc.2018.Vi.S (Browse shelf(Opens below)) Not for loan 01010110077732000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.25.M.Sc.2018.Vi.S (Browse shelf(Opens below)) 77732.CD Not for loan 01020110077732000

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biotechnology

Schistosoma mansoni and Schistosoma haematobium are parasitic flatworms that infect millions of people in developing countries. A recent report has proved that resistance of the water-rat to S. mansoni might be ascribed to arachidonic acid (ARA)-rich lipids in liver. Reports have shown that ARA is a safe and effective schistosomicide in vitro, and in vivo. Accordingly, it was proposed that ARA increased levels might be responsible for natural attrition of S. mansoni and S. haematobium in resistant rodents. Therefore, the levels of ARA in serum, lung, and liver of rats (resistant) and mice (susceptible) before and post infection with S. mansoni and between mice (semi-permissive) and hamster (susceptible) before and post infection with S. haematobium were compared. Significant (P<0.05) correlation was recorded between ARA content and rodent resistance to schistosomes, implicating ARA as an endoschistosomicide

Issued also as CD

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