Prognostic value of tumor thickness of buccal mucosa squamous cell carcinoma on the incidence of nodal metastasis in the neck : A cohort study / Mohamed Osama Mohamed Ibrahim Ghorab ; Supervised Mohamed Ahmed Farid Shehab , Hossam Abdelkader Elfol , Mohamed Atef Abdelrasoul

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Mohamed Osama Mohamed Ibrahim Ghorab

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TextLanguage: English Publication details: Cairo : Mohamed Osama Mohamed Ibrahim Ghorab , 2020Description: 129 P. : charts , facsimiles , photographs ; 25cmOther title:

تقييم استعمال سمك الورم فى توقع الانبثاث العنقى لسرطان الخليه الحرشفيه من الخد : دراسه الاتراب [Added title page title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Surgery Summary: Aim Out of the proposed prognostic factors in the literature to predict nodal metastases in N0 patients in head, tumor thickness or depth of invasion is highly regarded as reliable. In addition, the American Joint Committee on Cancer has issued its latest staging system in January 2017 with the incorporation of depth of invasion into the TNM staging system. This highlights the growing body of evidence of the importance of tumor thickness and depth of invasion of malignant tumors in the management of the disease.The most common cutoff value found in literature is 4 mm.(Huang, Hwang, Lockwood, Goldstein, & O{u2019}Sullivan, 2009)(Huang, Hwang, Lockwood, Goldstein, & O{u2019}Sullivan, 2009)(Huang et al., (2009) The rationale to conduct this research is to confirm that the Egyptian buccal squamous cell carcinoma patients falls within the literature suggested cutoff value. Methodology The study was conducted on 30 patients divided into two groups based on the 4mm cutoff value. Preoperative assessment with ultrasound for tumor thickness was done and followed by correlation with pathological specimen. The significant of using the 4 mm as a cut off point for predicting nodal diseases was studied. Result There was no statistically significant difference in age and gender distribution between both groups (P=0.983 and P=1.000, respectively). There was no statistically significant difference in the frequency of T stage between both groups (P=0.135). In the entire study, 10 patients (33.3%) showed nodal metastasis and 20 patients (66.6%) had negative nodes. In TT <4mm group, 2 patients (13.3%) had positive nodes and 13 patients (86.6%) had negative nodes; while in TT {u2265}4mm group, 8 patients (53.3%) had positive nodes and 7 patients (46.6%) had negative nodes

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Item type	Current library	Home library	Call number	Copy number	Status	Date due	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.09.13.M.Sc.2020.Mo.P (Browse shelf(Opens below))		Not for loan		01010110083495000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.09.13.M.Sc.2020.Mo.P (Browse shelf(Opens below))	83495.CD	Not for loan		01020110083495000

Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Surgery

Aim Out of the proposed prognostic factors in the literature to predict nodal metastases in N0 patients in head, tumor thickness or depth of invasion is highly regarded as reliable. In addition, the American Joint Committee on Cancer has issued its latest staging system in January 2017 with the incorporation of depth of invasion into the TNM staging system. This highlights the growing body of evidence of the importance of tumor thickness and depth of invasion of malignant tumors in the management of the disease.The most common cutoff value found in literature is 4 mm.(Huang, Hwang, Lockwood, Goldstein, & O{u2019}Sullivan, 2009)(Huang, Hwang, Lockwood, Goldstein, & O{u2019}Sullivan, 2009)(Huang et al., (2009) The rationale to conduct this research is to confirm that the Egyptian buccal squamous cell carcinoma patients falls within the literature suggested cutoff value. Methodology The study was conducted on 30 patients divided into two groups based on the 4mm cutoff value. Preoperative assessment with ultrasound for tumor thickness was done and followed by correlation with pathological specimen. The significant of using the 4 mm as a cut off point for predicting nodal diseases was studied. Result There was no statistically significant difference in age and gender distribution between both groups (P=0.983 and P=1.000, respectively). There was no statistically significant difference in the frequency of T stage between both groups (P=0.135). In the entire study, 10 patients (33.3%) showed nodal metastasis and 20 patients (66.6%) had negative nodes. In TT <4mm group, 2 patients (13.3%) had positive nodes and 13 patients (86.6%) had negative nodes; while in TT {u2265}4mm group, 8 patients (53.3%) had positive nodes and 7 patients (46.6%) had negative nodes

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