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049 _a-Depisied
082 _a610
097 _aPh.D
099 _aCai01.13.06.Ph.D.2022.He.p.
100 _aHeba Hamed Rashad
245 _aProspective phase ii study of hypofractionated short course radiation therapy folowed by neoadjuvant chemotherpy and surgery in locally advanced rectal cancer /
_cHeba Hamed Rashad ; Hisham El Husseiny ,Reem Emad , Marwa Hussein , Tarek ElBaradie.
260 _c2022.
502 _aThesis (Ph.D)-Cairo University,2022.
504 _aBibliography: p. 105-116.
520 _aUpfront neoadjuvant chemoradiation followed by surgery and adjuvant chemotherapy remained a standard of care for loclly advanced rectal cancers. However this strategy is associated with high rates of distant failure. Total neoadjuvant therapy with short course radiation therapy (SCRT) followed by full course of chemotherapy is investigated aiming for early treatment of micrometastasis and reducing rates of distant failure without compromising local control.
650 _aRadiationOncology
653 _aRadiation Therapy
700 _aReem Emad
856 _uhttp://172.23.153.220/th.pdf
905 _aMohamady
942 _cTH
_2ddc
999 _c164348
_d164348
336 _2rda content
_atext
337 _2rdamedia
_aUnmediated
338 _2rdacarrier
_avolume