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040 _aEG-GICUC
_beng
_cEG-GICUC
_dEG-GICUC
_erda
041 0 _aeng
_beng
_bara
049 _aDeposit
082 0 4 _a615.37
_221
092 _a615.37
_221
097 _aM.Sc
099 _aCai01.11.07.M.Sc.2022.Na.S
100 0 _aNada Waheed Ahmed Radwan,
_epreparation.
245 1 0 _aSerum soluble interleukin–2 receptor alpha and rantes chemokine as potential biomarkers for Covid–19 infection /
_cby Nada Waheed Ahmed Radwan ; Supervised by Prof. Dr. Dalia Ahmed Aly Labib, Prof. Dr. Rasha Mohamad Hosny Shahin.
246 1 5 _aمستوى مستقبلات IL-2 الذائبة و كيموكين RANTES فى الدم كمؤشرات حيوية لعدوى فيروس كورونا المستجد
264 0 _c2022.
300 _a102 pages :
_bIllustrations ;
_c25 cm. +
_eCD.
336 _2rdacontent
_atext
337 _2rdamedia
_aUnmediated
338 _2rdacarrier
_avolume
502 _aThesis (M.Sc.)-Cairo University, 2022.
504 _aBibliography: pages 88-100.
520 _aThe COVID 19 Pandemic has been a global emergency caused by the outbreak of SARS-CoV2 virus in Wuhan, Hubei, China in November 2019. The disease is characterized by acute respiratory distress among other symptoms produced by immune system disturbance and cytokine storm. Objective: To determine the serum level of soluble IL-2Ra and RANTES in COVID 19 patients and compare with healthy controls as well as detect correlation with disease severity. Methods: A case-control study was conducted on 60 patients with a positive nasopharyngeal swab tested by RealTime PCR for SARS- CoV2 admitted to isolation wards of Kasr Alainy Hospitals and COVID 19 outpatient clinics, and 25 healthy controls to measure serum levels of soluble IL-2Ra and RANTES using Enzyme Linked Immunosorbent Assay. Results: The results revealed no statistically significant difference in serum levels of soluble IL-2Ra and RANTES between patients and healthy controls, neither was there a difference in serum levels of both parameters between severe and non-severe cases of COVID 19.
520 _aتحديد مستوى مصل IL-2Ra القابل للذوبان و RANTES في مرضى COVID 19 ومقارنتها مع الضوابط الصحية وكذلك الكشف عن الارتباط مع شدة المرض. الطرق: أجريت دراسة الحالات والشواهد على 60 مريضا يعانون من تم اختبار مسحة البلعوم الأنفي الإيجابية بواسطة RealTime PCR لمرض السارس- تم إدخال CoV2 إلى أجنحة العزل بمستشفيات القصر العيني و عيادات خارجية لكوفيد 19 و25 مراقبة صحية للقياس مستويات مصل IL-2Ra و RANTES القابلة للذوبان باستخدام الإنزيم المرتبط مقايسة الامتصاص المناعي.
530 _aIssues also as CD.
546 _aText in English and abstract in Arabic & English.
650 0 _aSerum
_xCOVID-19
653 0 _asIL-2Ra
_aRANTES
_aCOVID 19
700 0 _aDalia Ahmed Aly Labib,
_ethesis advisor.
700 0 _aRasha Mohamad Hosny Shahin,
_ethesis advisor.
700 0 _aMohamed Gamal Elansary,
_ethesis advisor.
856 _uhttp://172.23.153.220/th.pdf
900 _b01-01-2022
_cDalia Ahmed Aly Labib
_cRasha Mohamad Hosny Shahin
_cMohamed Gamal Elansary
_UCairo University
_FFaculty of Medicine
_DDepartment of Clinical and Chemical Pathology
905 _aHanan
_eEssam
942 _2ddc
_cTH
_e21
_n0
999 _c165638
_d165638