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003			OSt
005			20241119161553.0
008			241117s2023 |||a|||fr|m|| 000 0 eng d
040			_aEG-GICUC _beng _cEG-GICUC _dEG-GICUC _erda
041	0		_aeng _beng _bara
049			_aDeposit
082	0	4	_a616.994
092			_a616.994 _221
097			_aM.Sc
099			_aCai01.19.04.M.Sc.2023.Ab.I
100	0		_aAbdelrahman Salah ElSobhy Mohamed, _epreparation.
245	1	0	_aImpact of Radiological Predictors on Surgical Management and Outcome of Carotid Body Tumor Resection / _cby Abdelrahman Salah ElSobhy Mohamed ; Supervised by Prof. Dr. Ayman Abdelwahab, Dr. Romany Esshak, Dr. Kareem Sallam.
246	1	5	_aتاثير المتنبآت الاكلينيكية و الاشعية علي نتائج المدى القصير بعد عملية استئصال ورم الجسم السباتي /
264		0	_c2023.
300			_a120 pages : _billustrations ; _c25 cm. + _eCD.
336			_atext _2rda content
337			_aUnmediated _2rdamedia
338			_avolume _2rdacarrier
502			_aThesis (M.Sc.)-Cairo University, 2023.
504			_aBibliography: pages 105-120.
520			_aCBTs represent more than half of neck paragangliomas, yet still a very rare cause of neck lumps. Like other paragangliomas, CBTs originate from the neural crest. These lesions are rare before the age of 20. Recent studies have reported that CBTs are more common in females rather than males (1.9:1) but, there are some Asian centers reporting their data vice versa. The mechanisms of carotid body tumor formation remain unknown, but since 1930 it has been accepted that the carotid body is a chemoreceptor which monitors the oxygen tension of systemic arterial blood. Thus carotid body tumors are associated with conditions producing chronic hypoxia, such as high altitude. CBT is one of the most commonly seen jugular paraganglioma involving the carotid body chemoreceptors, but rarely seen clinically, so the corresponding diagnosis and management remain difficult. They present a surgical challenge because of the frequent complications and difficulties caused by their high vascularity, proximity and possible infiltration of the carotid bifurcation, compression of cranial nerves in the neck, and extension to the skull base. CBTs are so rare that management recommendations based on the usual prospective trials or by meta- analysis are not practical. Because of the infrequent performance of CBT surgical procedures, individual surgeons or single institutions cannot accumulate a sufficient number of cases to report or evaluate their outcomes with statistical confidence. An attempt to predict the difficulties encountered during resection and the outcome of treatment at our institution was made by reviewing our experience of this rare disease. Objectives: To plan a radiological based surgical approach during CBT resection , analyze indications of vascular reconstruction, technique and types of vascular graft, outcomes following surgical intervention and the role of pre-operative embolization Patients and methods: A retrospective study which was conducted on all patients diagnosed with carotid body tumor (20 patients) attending the National Cancer Institute between January 2007 and November 2022 and underwent CBT resection inside the surgical department
520			_aيمثل العلاج السلوكي المعرفي أكثر من نصف الأورام العقدية العصبية في الرقبة، ومع ذلك لا يزال سببًا نادرًا جدًا لكتل ​​الرقبة. مثل أورام المستقتمات العقدية العصبية الأخرى، ينشأ العلاج السلوكي المعرفي من العرف العصبي. هذه الآفات كانت نادرة من قبل سن 20. أفادت الدراسات الحديثة أن العلاج السلوكي المعرفي أكثر شيوعًا عند الإناث منه الذكور (1.9:1) ولكن هناك بعض المراكز الآسيوية تنشر بياناتها بالعكس. لا تزال آليات تشكل ورم الجسم السباتي غير معروفة، لكنها كانت كذلك منذ عام 1930 من المقبول أن الجسم السباتي هو مستقبل كيميائي يراقب توتر الأكسجين الدم الشرياني الجهازي. وهكذا ترتبط أورام الجسم السباتي بالظروف المنتجة نقص الأكسجة المزمن، مثل الارتفاعات العالية.
530			_aIssued also as CD
546			_aText in English and abstract in Arabic & English.
650		7	_aSurgical Oncology _2qrmak
653		0	_aCarotid body tumor _aVascular reconstruction _aVascular grafts _aCarotid artery resection _aCarotid bypass
700	0		_aAyman Abdelwahab _ethesis advisor.
700	0		_aRomany Esshak _ethesis advisor.
700	0		_aKareem Sallam _ethesis advisor.
900			_b01-01-2023 _cAyman Abdelwahab _cRomany Esshak _cKareem Sallam _UCairo University _FFaculty of National Cancer Institute _DDepartment of Surgical Oncology
905			_aEman _eHuda
942			_2ddc _cTH _e21 _n0
999			_c168888