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008			250112s2024 |||a|||f m||| 000 0 eng d
040			_aEG-GICUC _beng _cEG-GICUC _dEG-GICUC _erda
041	0		_aeng _beng _bara
049			_aDeposit
082	0	4	_a617.73
092			_a617.73 _221
097			_aPh.D
099			_aCai01.11.24.Ph.D.2024.Ki.P
100	0		_aKirollos Joseph Guirguis Escander, _epreparation.
245	1	0	_aPeripapillary vascular tortuosity index as a sign of stasis precipitating retinal vein occlusion in primary glaucomas / _cby Kirollos Joseph Guirguis Escander ; Supervision of Prof. Sherif Aly Gamal El-Din, Prof. Dr. Ahmed Abdallah Mohalhal, Dr. Alaa El-Din Abdelsalam Fayed.
246	1	5	_a/ مؤشر انحراف الأوعية الدموية المحيطة بالعصب البصري كعلامة على الركود المؤدي إلى انسداد الوريد الشبكي في المياه الزرقاء الأولية
264		0	_c2024.
300			_a93 pages : _billustrations ; _c25 cm. + _eCD.
336			_atext _2rda content
337			_aUnmediated _2rdamedia
338			_avolume _2rdacarrier
502			_aThesis (Ph.D)-Cairo University, 2024.
504			_aBibliography: pages 78-93.
520			_aBackground: Retinal vein occlusion (RVO) is one of the most common retinal vascular disorders. It is associated with the occurrence of glaucoma as one of its main risk factors. The exact pathogenesis is unknown, however several theories state that the vascular stasis precipitating venous occlusion may result from external compression, vascular obstruction, or vascular wall pathology. Methods: This study was an observational, cross-sectional, case control study aiming at the evaluation of retinal peripapillary vascular tortuosity index (VTI) using OCT-A images as a sign of vascular stasis. 45 eyes were equally distributed among three study groups; healthy controls, glaucomatous eyes with no RVO and glaucomatous eyes with unilateral RVO. We also studied their OCT-A scans to obtain the vessel density of the peripapillary and macular capillary plexuses for evidence of capillary non-perfusion. Results: Our study revealed a statistically significant difference in the VTI among the three groups (p-value < 0.001); the highest VTI was in the glaucoma + RVO group (1.13 ± 0.02, 1.16 ± 0.02) followed by the glaucoma with no RVO group (1.06 ± 0.01, 1.07 ± 0.01) and at last the healthy control group (1.04 ± 0.01, 1.05 ± 0.01).The vessel density was significantly less in the macular superficial capillary plexuses in glaucomatous compared to non-glaucomatous eyes, but deep capillary plexuses showed no statistically significant difference. Conclusion: Primary glaucomas contribute to higher levels of peripapillary vascular stasis manifested by increased vascular tortuosity. This may precipitate retinal vein occlusion in these eyes even in the absence of other classic cardiovascular risk factors
530			_aIssues also as CD.
546			_aText in English and abstract in Arabic & English.
650		7	_aVisual and retinal nerve diseases _2qrmak
653		0	_aRetinal vein occlusion _avascular tortuosity index _aprimary glaucomas _aperipapillary _aOCT-A _asuperficial capillary plexus _adeep capillary plexus
700	0		_aSherif Aly Gamal El-Din _ethesis advisor.
700	0		_aAhmed Abdallah Mohalhal _ethesis advisor.
700	0		_aAlaa El-Din Abdelsalam Fayed _ethesis advisor.
900			_b01-01-2024 _cSherif Aly Gamal El-Din _cAhmed Abdallah Mohalhal _cAlaa El-Din Abdelsalam Fayed _UCairo University _FFaculty of Medicine _DDepartment of Ophthalmology
905			_aShimaa _eHuda
942			_2ddc _cTH _e21 _n0
999			_c170157