000 019780000a22003250004500
003 EG-GICUC
008 061212s2006 ua d f m 000 0 eng d
040 _aEG-GICUC
_beng
_cEG-GICUC
041 0 _aEng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.07.Ph.D.2006.Za.G.
100 0 _aZainab Ali Hassan
245 1 0 _aGeneration of Dendritic Cells from Acute Myeloid Leukemic Blasts Using IL - 4 and GM - CSF /
_cZainab Ali Hassan ; Supervised Tayssir Kamel Eyada , Hala Gabr Metwally , Iman Ali Attia
246 1 5 _aانتاج الخلايا المتفرعة من الخلايا السرطانية لسرطان الدم الميلودى الحاد باستخدام انترلوكين فور و عامل حث مستعمرات الخلايا المحببة ووحيدة الخلية
260 _aCairo :
_bZainab Ali Hassan ,
_c2006
300 _a230 P :
_bcharts ;
_c25cm
502 _aThesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology
520 _aEffective presentation of tumor antigens is fundamental to strategies aimed at enrolling the immune system in eradication of residual disease after conventional treatment Myeloid malignancies provide a unique opportunity to drive DCs functioning APCs from malignant cells themselves This study aimed at producing of DCs from AML blasts using IL - 4 and GM - CSF Sixteen cases out of 20 cases generated DCs from AML blasts using IL - 4 and GM - CSF with the highest change with IL - 4 The highest viability was with GM - CSF and the highest DCs count and morphologically differentiated DCs were with both cytokines
530 _aIssued also as CD
653 4 _aAML
653 4 _aAPCs
653 4 _aDendritic cells
700 0 _aHala Gabr Metwally ,
_eSupervisor
700 0 _aIman Ali Attia ,
_eSupervisor
700 0 _aTayssir Kamel Eyada ,
_eSupervisor
905 _aAml
_eCataloger
905 _aEsam
_eRevisor
942 _2ddc
_cTH
999 _c26913
_d26913