| 000 | 02100cam a2200337 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 008 | 100224s2010 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.08.05.Ph.D.2010.Ma.S | ||
| 100 | 0 | _aMarwa Galal Eldin Elgazzar | |
| 245 | 1 | 0 |
_aSynthesis of new pyrrole pyrazole pyrimidine and pyrrolopyrimidine derivatives carrying a sulfonamide moiety of expected antitumor activity : _bwith studying the synergistic effect of y - irradiation / _cMarwa Galal Eldin Elgazzar ; Supervised Fatma Abdelfattah Ragab , Mostafa Mohamed Soliman Ghorab , Helmi Ismail Heiba |
| 246 | 1 | 5 |
_aتشييد مشتقات البيرول : البيرازول : البيريميدين والبيرولوبيريميدين الجديدة والتى تحتوى على مجموعة السلفوناميد المتوقع لها نشاطا كمضادلت للسرطان : _bودراسة التأثير التحفيزى للتشعيع الجامى |
| 260 |
_aCairo : _bMarwa Galal Eldin Elgazzar , _c2010 |
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| 300 |
_a164 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry | ||
| 520 | _aIn a search for new cytoloxic agents with improved antitumor activity some new pyrrole pyrazole pyrimidine and pyrrolo [2,3-d] pyrimidine derivatives bearing sulfonamide moiety were synthesized . All the newly synthesized compounds were subjected to in - vitro cytotoxic screening also the synergism of the synthesized compounds with radiation was studied . These new compounds were docked in the active site of the carbonic anhydrase enzyme | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aPyrazole | |
| 653 | 4 | _aPyrimidine | |
| 653 | 4 | _aSulfonamide | |
| 700 | 0 |
_aFatma Abdelfattah Ragab , _eSupervisor |
|
| 700 | 0 |
_aHelmi Ismail Heiba , _eSupervisor |
|
| 700 | 0 |
_aMostafa Mohamed Soliman Ghorab , _eSupervisor |
|
| 902 | _a1 | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aSoheir _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c29529 _d29529 |
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