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| 003 | EG-GiCUC | ||
| 005 | 20250223030300.0 | ||
| 008 | 100926s2010 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.12.02.Ph.D.2010.Fa.A | ||
| 100 | 0 | _aFatma Baiuomy Rashedy Abdallah | |
| 245 | 1 | 0 |
_aAntibody directed enzyme prodrug therapy : _bMolecular studies on carboxypeptidase G2 , production by DNA shuffling of novel variants of CPG2 for more efficient cancer treatment / _cFatma Baiuomy Rashedy Abdallah ; Supervised Abdalla M. Negm , Ahmed I. Amien |
| 246 | 1 | 5 |
_aعلاج مرض السرطان بإستخدام جسم مضاد موجه ومحمل بإنزيم الكربوكسى بيبتيديزجى2 : _bدراسات جزيئية على هذا الانزيم : وانتاج مشابهات لهذا الانزيم ذو كفاءة اعلى من خلال تكنولوجيا قص وخلط وإعادة لصق الجين |
| 260 |
_aCairo : _bFatma Baiuomy Rashedy Abdallah , _c2010 |
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| 300 |
_a246P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry | ||
| 520 | _aGlucarpidase (former name : carboxypeptidase G2, or CPG2 ) is a bacterial enzyme that is widely used in detoxification of the cytotoxic drug methotrexate and in Antibody Directed Enzme Prodrug Therapy ( ADEPT ) for cancer treatment . In this study we report three achievements in relation to the CPG2 enzyme and the ADEPT for cancer treatment | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aADEPT | |
| 653 | 4 | _aCPG2 overexpression | |
| 653 | 4 | _aSynthetic carboxypeptidase G2 | |
| 700 | 0 |
_aAbdalla M. Negm , _eSupervisor |
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| 700 | 0 |
_aAhmed I. Amien , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aFatma _eCataloger |
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| 905 |
_aNazla _eRevisor |
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| 942 |
_2ddc _cTH |
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| 999 |
_c31480 _d31480 |
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