000 022810000a22003610004500
003 EG-GICUC
005 20250223030446.0
008 060917s2006 ua a f m 000 0 eng d
040 _aEG-GICUC
_beng
_cEG-GICUC
041 0 _aEng
049 _aDeposite
097 _aPh.D
099 _aCai01.12.08.Ph.D.2006.Mo.A.
100 0 _aMohamed Abou El - Abbas Embaby
245 1 0 _aAnalytical studies on some marine toxins as a source of bioactive compounds /
_cMohamed Abou El - Abbas Embaby ; supervised Mahmoud Sabri Rizk , Ahmad Mahmoud Farag , Mohamed Nasr El - Deen Gomaa
246 1 5 _aدراسات تحليلية على بعض السموم البحرية كمصدر لمواد ذات نشاط بيولوجى
260 _aCairo :
_bMohamed Abou El - Abbas Embaby Ibrahim ,
_c2006
300 _a135L :
_bill ;
_c30cm
502 _aThesis (PH.D.) - Cairo University - Faculty Of Science - Department Of Analytical Chemistry
520 _aThe present study has been carried out to detect the presence of low molecular weight bioactive compound (s) in the extract of some marine invertebrates collected from the Red Sea environmentThe crude extracts of the collected samples were subjected to different bioassay techniques such as mouse bioassay , brine shrimp , antimicrobial , antifungal , antiviral and Acetylcholine esterase inhibitionThe chemical studies of the Gyrostoma helianthus lead to isolation of two toxic fractions with two different modes of actionThe first toxic fraction inhibited the activity of Acetylcholine esterase and the second toxic fraction was k+potassium channel blockerThe bioactive compound (AchE inhibitor) was isolated in a pure form using HPLC and its chemical structure was elucidated using different spectroscopic techniquesThe toxicokinetics of the AchE inhibitor isolated bioactive compound was studie
530 _aIssued also as CD
653 4 _aAnticancer
653 4 _aAntiviral
653 4 _aBioactivity
653 4 _aMarine Toxins
700 0 _aAhmad Mahmoud Farag ,
_esupervisor
700 0 _aMahmoud Sabri Rizk ,
_esupervisor
700 0 _aMohamed Nasr El - Deen Gomaa ,
_esupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aEnas
_eCataloger
905 _aMustafa
_eRevisor
942 _2ddc
_cTH
999 _c35111
_d35111