000 01899cam a2200337 a 4500
003 EG-GiCUC
005 20250223030520.0
008 111122s2011 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.05.M.Sc.2011.He.S
100 0 _aHebat Allah Mohamed Sobhi Elsaid Agha
245 1 0 _aSynthesis and antitumor evaluation of some new N⁴ substituted sulfapyridine derivatives with studying the synergistic effect of y-irradiation /
_cHebat Allah Mohamed Sobhi Elsaid Agha ; Supervised Fatma Abdelfattah Ragab , Mostafa Mohamed Soliman Ghorab
246 1 5 _aتحضير بعض مشتقات N⁴ السلفابيردين لتقييمها كمضدات للأورام السرطانية مع دراسة التأثير التحفيزى للتشعيع الجامى
260 _aCairo :
_bHebat Allah Mohamed Sobhi Elsaid Agha ,
_c2011
300 _a142 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry
520 _aThe aim of the present investigation is to synthesize a new class of N⁴ substituted sulfapyridine derivatives with anticipated cytotoxic activity. All the newly synthesized compounds were screened for their in-vitro cytotoxic activity against breast cancer cell line (MCF-7) compared to the reference drug Doxorubicin. Also the synergism of the most potent synthesized compounds with y-irradiation was studied
530 _aIssued also as CD
653 4 _aCytotoxic activity
653 4 _aSulfapyridine
653 4 _ay-irradiation
700 0 _aFatma Abdelfattah Ragab ,
_eSupervisor
700 0 _aMostafa Mohamed Soliman Ghorab ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aEnas
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c36338
_d36338