000 01719cam a2200313 a 4500
003 EG-GiCUC
008 120916s2012 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.04.M.Sc.2012.Ya.N
100 0 _aYara Raafat Milad Mohareb
245 1 0 _aNew approaches for the synthesis of thiophene derivatives and their biological evaluation /
_cYara Raafat Milad Mohareb ; Supervised Afaf Kamal Eldeen Elansary , Mona Monir Kamel
246 1 5 _aطرق مبتكرة لتحضير مشتقات الثيوفين ودراسة نشاطها البيولوجى
260 _aCairo :
_bYara Raafat Milad Mohareb ,
_c2012
300 _a114Leaves :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry
520 _aThis thesis comprises literature survey on the synthesis of new thiopene derivatives for evaluation as anti - tumor agents through the inhibition of Protein Tyrosine Kinase ( PTK ) including the methods used for their synthesis and a brief outline on their pharamacological importance . The thesis includes four chapters: The first chapter is an introduction to the pharmacology of reported thiophenes that have anti - tumor activity by inhibition of Protein Tyrosine Kinase enzyme comprising mainly tetrahydro [ 1 ] benzothiophene
530 _aIssued also as CD
653 4 _aPyrazole
653 4 _aPyridine
653 4 _aThiophene
700 0 _aAfaf Kamal Eldeen Elansary ,
_eSupervisor
700 0 _aMona Monir Kamel ,
_eSupervisor
905 _aFatma
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c39513
_d39513